Author: Hongge comes from Medical Wechat WeChat official account.

　 　　 　　　Recent epidemic situation in ChinaIn the process of getting up, there are some situations that deserve our attention.the most importantIsFalse negatives in nucleic acid detection. Intercepting relevant news, it was found that 8 confirmed patients in Shijiazhuang on the 22nd were repeatedly negative for nucleic acid detection, and 5 confirmed patients in Shijiazhuang on the 24th were repeatedly negative for nucleic acid detection.

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　 　On the 22nd, there were 11 new confirmed cases in Shijiazhuang, including:

Case 1: Male, 52 years old, from Huangjiazhuang Village. On the evening of 21st.Ninth nucleic acid positive;

Case 2: Male, 13 years old, Niujiazhuang Village. On the evening of the 21st.Nine times nucleic acid positive;

Case 3: Female, 11 years old, Zhongyao Village. On the evening of the 21st.Nine times nucleic acid positive;

Case 4: Male, 49 years old, Nanqiaozhai Village. On the evening of 21st.Ninth nucleic acid positive;

Case 5: Male, 47 years old, Niujiazhuang Village. On the evening of 21st.Ninth nucleic acid positive;

Case 6: Female, 65 years old, Niujiazhuang Village. On the evening of 21st.Ninth nucleic acid positive;

Case 7: Male, 11 years old, grandson of Case 6. On the evening of 21st.Ninth nucleic acid positive;

Case 11: Male, 67 years old, Xiaoguozhuang Village, husband of Case 2 on January 7th. On January 3, it was transferred to centralized isolation medical observation; On the evening of 21st.11th nucleic acid detectionFinally positive;

On the 24th, there were 7 new confirmed cases in Shijiazhuang:

Case 1: Female, 65 years old, Nanqiaozhai Village. Centralized isolation on the 11 th.Nucleic acid after 9 times, 22 positive.

Case 2: Female, 4 years old, Nanqiaozhai Village. Centralized isolation on the 11 th.Nucleic acid after 9 times, 22 positive.

Case 3: Female, 4 years old, Mi Jie, Chang ‘an District. Centralized isolation on the 13 th.Nucleic acid after 8 times, 23 positive.

Case 4: Female, 64 years old, Xiaoguozhuang Village. Centralized isolation on the 10 th.After 11 nucleic acids, 24 positive.

Case 5: Male, 34 years old, Xiaoguozhuang Village. Centralized isolation on the 8 th.After 11 nucleic acids, 24 positive.

Case 6: 34-year-old female, Liujiazuo Village, was positive for nucleic acid on the 5th, was diagnosed as asymptomatic infection on the 6th, and was clinically confirmed on the 24th.

Case 7: A 28-year-old male, living in Yuhua District, went to work by car at Zhengding Airport on weekdays. He was diagnosed as asymptomatic infected with nucleic acid on the 5th, and was clinically confirmed on the 24th.

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Since the outbreak of COVID-19 last year, the topic of high false negative rate of nucleic acid detection has been the focus of attention. It has been reported that the positive rate of Covid-19 detection by fluorescence quantitative RT-PCR is only 30%-50% at present, which leads to extremely high false negative rate.

For Hongge, who doesn’t know much about the test, this paper analyzes the relatively high false negative test by searching articles and documents, and summarizes some reasons to discuss with you.

First, the incidence of COVID-19 suggests that it is highly possible to collect positive samples in a proper time.

Academician Yuan Guoyong’s team conducted this cohort study in Hong Kong Princess Margaret Hospital and Queen Mary Hospital. From January 22 to February 12, 2020, 23 hospitalized patients who were diagnosed as COVID-19 by laboratory examination of nasopharyngeal or sputum specimens were screened in the two hospitals.

A total of 173 respiratory specimens were collected from 23 patients. The researchers used RT-QCPR to determine the viral load in the samples. The results showed that the median viral load of respiratory tract samples was 5.2 log10 copies /mL (interquartile range was 4.1-7.0), and only 3 patients (13%) did not detect Covid-19 RNA in saliva samples.

The researchers observed that,The viral load in saliva was the highest in the first week after the patient developed symptoms, and then gradually decreased.Eight days after the patient developed symptoms, airway extracts were collected, and there was no obvious downward trend in viral load. Of the 21 patients who did not die,Seven people (33%) could still detect viral RNA after 20 days of symptoms, but this was not related to the severity of the disease.

▲ Changes of viral load in saliva (blue line) and airway extract (red line) of all 23 patients. Abscissa D- days after symptoms appear; S/E- number of saliva/airway samples.

AprilAccording to a study published in Nature Medicine, COVID-19 patients are most infectious before symptoms appear, and they begin to shed SARS-CoV-2 2 2-3 days before the first symptoms appear.

https://doi.org/10.1038/s41591-020-0869-5

The study, led by Eric Lau of the University of Hong Kong, involved 94 patients with COVID-19 admitted to the Eighth People’s Hospital of Guangzhou, China, 50% of whom were male, with a median age of 47 years. Among them, 61 of 93 patients were mild. Specifically, the researchers collected the throat swabs of 94 COVID-19 patients who were treated in the Eighth People’s Hospital of Guangzhou, China from January 21st to February 14th. From the onset of symptoms to 23 days after onset, 414 throat swabs were collected.

The results show that the researchers areThe high viral load was detected shortly after the patient developed symptoms, and then gradually decreased to the detection limit around the 21st day.There is no significant difference in viral load among different sexes, age groups and disease severity.

In addition, the researchers also analyzed 77 samples of "transmission pairs" from public data to assess how much time passed between the onset of symptoms in each patient. It assumes that the median incubation period (the time from infection to symptoms) is 5.2 days.The research team concluded that infectivity began 2.3 days before symptoms appeared, and peaked 0.7 days before symptoms appeared.

In the sensitivity analysis, the same estimation procedure is used, but assuming that the infectious attack is unchanged 1-7 days before the symptom occurs, thenIt was found that the infectivity reached its peak 0-2 days before the onset of symptoms, and the transmission ratio before the onset of symptoms was 46% to 55%.

The study also found that,The virus may start shedding 2-3 days before the first symptoms appear.After the symptoms appear, the viral load in the patient’s body decreases faster. This is consistent with the results of two recent studies. On April 1st, teams from Munich, Germany, Berlin and Cambridge, England published the article "Viro logical assessment of hospital patients with Covid-2019" on Nature. It was found that the shedding peak of Covid-19 occurred in the early upper respiratory tract infection.This shows that virus carriers may be the most infectious when they have mild symptoms or almost no obvious symptoms.

Brother Hong:From the above two documents, we can draw a conclusion that the virus shed and spread 2-3 days before the symptoms appear after infection, and after the symptoms appear, with the passage of time,The viral load of throat swab decreases gradually, and the viral load detected within 7 days after symptoms. If symptoms have existed for more than 20 days, the reliability of negative conclusion of throat swab is poor.

Solution:We need to publicize the law of the new crown to the people and medical workers, and improve our vigilance against COVID-19. It is best for patients to see a doctor in time, and doctors can also suspect this possibility. Only at the right time can we collect high-content samples and diagnose and control them in time.

Second, accurate sampling strategy is the best means to reduce false negative results.

In February, a study published by Medrxir, a pre-printed website, collected respiratory tract samples such as nasal swab, throat swab, sputum and bronchoalveolar lavage fluid (BALF) from patients diagnosed with COVID-19, and included 213 Covid-19-infected patients admitted to the Third People’s Hospital of Shenzhen from January 11th to February 3rd, 2020, who were diagnosed by Guangdong CDC. A total of 866 respiratory tract samples, including 490 nasal swabs, 205 throat swabs, 142 sputum samples and 29 BALF samples, were collected at the time of admission and after each time point. According to the collection date, the samples were divided into 0~7 days, 8~14 days and ≥15 days after onset. According to the guidelines on prevention and treatment of Covid-19 infection issued by National Health Commission, patients were divided into severe and mild cases.

Three groups were divided according to the sample collection time after onset, and the viral nucleic acid was quantitatively determined.The positive rate of viral nucleic acid in sputum samples was the highest in the group of 0~7 days after onset.The positive rates of severe and mild cases were 88.9% and 82.2% respectively.Followed by a nasal swab.(73.3% and 72.1% respectively),The throat swab again.(60.0% and 61.3% respectively). In mild cases, the positive rate of nasal swab and sputum samples is similar.

The positive rate of BLAF samples collected from 8 to 14 days after the onset of severe cases was 100%.However, the BALF samples of 3 mild cases were negative. In all cases, the positive rate of sputum samples was the highest in the 8~14 days after onset, which was much higher than that of nasal swab and throat swab. It is worth noting that the positive rate of throat swab in severe patients is only 50%, and that in mild patients is only 29.6%.

In the group ≥15 days after onset,The positive rates of BALF, sputum and nasal swab from severe cases were similar. In mild cases, the positive rate of sputum and nasal swab is similar, which is much higher than that of throat swab.

For the diagnosis of viral nucleic acid in COVID-19’s patients,Sputum samples are the most accurate, followed by nasal swabs. It is not recommended to collect throat swabs for diagnosis.

The difference between oropharyngeal swab and nasopharyngeal swab

anusswab

Brother Hong:

1. Oropharyngeal swab is the least painful and most acceptable, but it has to bear the consequences of high false negative results. My suggestion is to use it according to the epidemic risk in the first epidemic area.

2. The positive rate of nasopharyngeal swab is higher than that of oropharyngeal swab, which is why nasopharyngeal swab is introduced into laboratory examination in the fifth edition of Diagnosis and Treatment Plan for Pneumonia Infected by Covid-19 (the fourth edition is still pharyngeal swab). If we want to pursue accuracy, it is suggested to use it, or to use it when screening people in close contact or sub-close contact. At present, the examination of returnees in domestic reports seems to be nasopharyngeal swab method.

3. Alveolar lavage fluid can’t be used for screening in the general population, so it is suggested that hospitals with ICU should use it for screening severe pneumonia patients living in ICU for COVID-19 patients.

4. Deep expectoration seems to be the best sample, but many patients in COVID-19 have a dry cough, which may not be possible.

5、anusSwabs were used in Daxing epidemic in Beijing, which is the first time to use this method in the screening process. In some literatures,anusAlthough the positive rate of swabs is not high, as I remember, it seems to be more than 10%, but it does not seem to coincide with the patients with oropharyngeal swabs, suggesting that the virus may attack the gastrointestinal tract, and also suggesting that there may be the possibility of gastrointestinal transmission in Covid-19. Although the initial symptoms of some patients are gastrointestinal symptoms such as abdominal pain and diarrhea, there are also ACE2 receptors in the digestive tract, which is theoretically possible, but it has not been confirmed at present. So,anusMy suggestion is that swabs can only be used as a supplement to nasopharyngeal swabs, and it is better to select patients whose first symptoms are digestive tract symptoms more accurately, which is unlikely to be used as a means of large-scale screening.

Solution:It is best for National Health Commission to issue a guiding document for large-scale screening, and make detailed regulations on what population and what sampling methods to adopt under what circumstances.,When local governments encounter an outbreak in COVID-19, it’s best to ask professionals to act as consultants and make choices according to the actual situation.

Third, the consistency of sampling ability of sampling personnel affects the sampling results.

Garbage in, garbage out (garbage samples produce garbage results), which is a sentence that inspectors often say.

The sampling team is huge, and the ability of sampling personnel must be uneven. In addition, people may have such fears about sampling, which often leads to unqualified samples.

Generally, there is an internal standard in the molecular diagnostic reagent to monitor the detection process, for example, RNaseP is used as the internal standard. If both the sample response curve and the internal standard response curve displayed by the fluorescence PCR platform do not jump, it means that the quality of the collected samples may have problems or false negatives may occur due to improper experimental operation, which needs to attract the attention of medical workers. The RNaseP internal standard can monitor the sample collection and ensure the accuracy of the test results.

Note: RNaseP is ribonuclease P, which is one of the most important ribozymes in human body. It is ubiquitous in all organs, tissues and cells of human body, and can detect RNA nucleic acid fragments from human body samples, and can also be used as an internal standard.

And I privately asked the relevant person in charge of our city’s temporary inspection center. He told me that every day in our hospital, some samples were told that they needed to be re-sampled because the internal standard did not jump. Imagine that you didn’t wipe down a few cells in your throat swab collection, so will the negative of this nucleic acid be accurate?

Solution:Consistency training for nucleic acid sampling personnel will greatly reduce the human influence, and it is easier to standardize the sampling process by taking such sampling methods as nasopharyngeal swab. Our city seems to have trained the nucleic acid emergency sampling team very early. What about your city?

In addition, if in the environment of large-scale nucleic acid sampling, when testing under the standard of 5-mixed 1 and 10-mixed 1, according to the above principle of internal standard, it seems that there is no single-tube ability in the quality control of internal standard. Therefore, especially those in the emergency sampling team, we must pay attention to the standard sampling methods and remember to collect qualified samples as much as possible.

Fourth, choose the right oneSampling device

The virus preservation tube mainly consists of a sampling swab and a virus nucleic acid preservation tube (containing virus nucleic acid preservation solution). There are many kinds of virus preservation tubes on the market at present.It is very important for epidemic prevention and disease diagnosis to choose the appropriate virus preservation tube, reduce the infection risk of medical inspectors as much as possible, and keep the virus RNA stable without degradation..

The preservation solution UTM used in traditional virus collection tubes is based on Hank’s solution, with gentamicin, fungal antibiotics, BSA (V), cryoprotectant, biological buffer and amino acids added. Its main purpose is to maintain the virus activity within a certain temperature range, so that it is convenient for health and epidemic prevention departments to further isolate, culture and trace the virus and determine the pathogen. This kind of non-inactivated tube, which I call it, is good for further work, but the sameLive virus increases the infection risk of medical staff in the whole process of sample collection, transportation and testing!Personally, I think this kind of sampling tube for inactivated virus should be a better choice for disease control sampling.

And clinicalIn order to achieve the purpose of rapid detection, it is not necessary to cultivate the virus, but only to crack the virus, so as long as the integrity and stability of the virus nucleic acid can be guaranteed.nowCommonly known as inactivation tube.Many inactivation tubes in China are used.The inactivation component is guanidine salt, which is in this inactivation tube in our hospital.Guanidine salt can crack the virus, but it can’t protect the integrity of nucleic acid for a long time.The virus nucleic acid may have been degraded during the delivery of the sample to the laboratory, which will also cause a "false negative" in the detection. Many studies show that both temperature and time can affect the test results, so the COVID-19 Laboratory Testing Guide has clear requirements for samples to be tested within 24 hours after collection and transported at 4 degrees Celsius. If it is necessary to exceed 24 hours, it should be stored at -70 degrees Celsius.

And some manufacturers put forward another inactivation tube, a kind of.containNon-guanidine saltThe virus preservation tube containing protein denaturant can inactivate the virus and ensure the preservation of virus nucleic acid at room temperature.And the virus nucleic acid is stably stored for 7 days.Does not degrade.

Solution:

1, from sampling to testing, it is necessary to mark the time, so that quality control can be carried out on the preservation time, which is basically no problem in a better hospital.

2. For the front-line staff to do the corresponding training, they should know the advantages and disadvantages of various types of preservation tubes and adopt the best sampling tubes suitable for local conditions.

3. It is best for the country to recommend the selection of sampling tubes with the support of relevant experimental data.

5. Failure of reagents caused by virus mutation?

After the virus mutation in South Africa, Britain, Brazil and other places, there have been cases that turned positive after ten tests in various parts of the world, including China.The FDA recently warned that virus mutation has caused some reagents to fail, and listed several kits that may be affected by mutation. This means that virus mutation may have led to the failure of some nucleic acid detection or persistent false negative.

The FDA listed several kits that may be affected by mutation:

Accula SARS-Cov-2 detection (Mesa Biotech): If the virus mutates at the 28881st base (GGG to AAC), the detection of this kit will be affected;

TaqPath COVID-19 Combo Kit (Thermo Fisher Scientific): This kit detects three genes at the same time, and the variant B.1.1.7 appearing in Britain will affect one of the detection results;

Linea COVID-19 detection (Applied DNA Sciences): This kit detects two genes at the same time, and the variant B.1.1.7 appearing in Britain will affect one of the detection results;

Helix, an American company doing nucleic acid detection, also noticed the influence of virus mutation on detection. The company’s nucleic acid detection simultaneously detected three Covid-19 genes: ORF1ab, N, and S. Because the B.1.1.7 strain that appeared in Britain had deletion mutation in S gene, ORF1ab and N could be detected in the detection, but S gene could not be detected (4). This phenomenon is called "S gene withdrawal".

In addition, the sensitivity of reagents from different manufacturers to COVID-19 is different, and the country also organized a national evaluation of reagents last year. butIn an evaluation study on the consistency and detection ability of seven domestic novel coronavirus nucleic acid detection kits published by Chinese Journal of Laboratory Medicine in July, 2020, it was proposed that "some kits have poor detection ability for weakly positive samples,It is suggested that weak positive samples should be rechecked by kits from at least two manufacturers to ensure the accuracy of the results."

Several targets of nucleic acid detection in Covid-19 are ORF1ab gene, N gene and S gene.

In the Technical Guide for Laboratory Detection of Pneumonia Infected in novel coronavirus issued by China CDC (hereinafter referred to as the Technical Guide), the two targets of nucleic acid detection in Covid-19 are ORF1ab gene and N gene respectively.

On January 6th, the Weekly Report of China Center for Disease Control and Prevention published the results of gene sequencing analysis of two cases of Covid-19 infection in Shijiazhuang and Xingtai. According to the published results, the strain prevalent in Gaocheng, Hebei Province, is different from the strain found in other places in China recently, and is homologous to the strain reported in Russia last July, belonging to strain B.1.1.123

Coincidentally, the mutation happened at the 28881 ~ 28883 bases of the virus gene of this strain, and this is exactly the position of the forward primer of the N gene!

This also explains why there were many negative results at that time.

I guess this is one of the reasons why the criteria for judging nucleic acid positivity have also changed.The judgment position that the single target is still positive after retest is positive.

Figure/Current Criteria for Judging Positive Cases in Technical Guide

Solution:

1. Require manufacturers of nucleic acid reagents to conduct confirmatory experiments on the current mutant strains and propose technical solutions.

2, all localities should introduce at least two kinds of better quality detection reagents, for control use.

3. Information about the failure of test reagents that may be caused by mutated viruses should be effectively and widely reported in domestic laboratories.

Six, the standard implementation in the process of laboratory testing

the pastAccording to the guidelines issued by relevant institutions, the collected samples need to be inactivated at 56℃ before nucleic acid detection, which is very likely to degrade the Covid-19 nucleic acid, which will lead to the failure of normal detection and ultimately improve the false negative rate.In the early daysInactivation treatment is carried out for the sake of biological safety, to protect the staff engaged in testing from virus infection.

But later, there were many voices of doubt in the academic circles, becauseViral RNA is easily degraded by ribonuclease, because this enzyme has the highest activity at 60℃. Ribonuclease comes from two aspects, one is the sample cells, and the other is the foreign pollutants in the process of collection, preservation and transportation.

Last February, there was a similar research article.The high-temperature inactivation process before virus nucleic acid extraction significantly reduces the amount of detectable virus nucleic acid templates, which has been pre-published on the platform of scientific papers of China Academy of Sciences.

And last May,The Journal of Clinical Chemistry published the research of Chinese scholars on Covid-19’s false negative test.The study confirmed that,Thermal inactivation can cause the increase of Ct value reflected by PCR and cause false negative results.Specifically, 46.7%(7/15) of the weakly positive samples were false negative after inactivation (a surprising proportion). Another inactivation method is to inactivate the virus by dissolving the virus protein with guanidine hydrochloride. This study confirmed that guanidine hydrochloride had little effect on PCR reaction, and the false negative rate was low, although there was also a false negative rate of 13.3%(2/15).

Related address: https://academic.oup.com/clinchem/article/66/6/794/5815979

I also inquired whether there was a 56-degree inactivation step in the detection process of CDC in the United States. Although my English ability was poor, I didn’t see this step by machine translation.

Including some other documents retrieved, it is also very clear that 56-degree inactivation does have a great influence on weakly positive specimens.

No matter the Manual of Nucleic Acid Detection in Medical Institutions in novel coronavirus (Trial) on July 13th, 2020 or the Manual of Nucleic Acid Detection in Medical Institutions in novel coronavirus (Trial 2nd Edition) on December 30th, 2020, there are corresponding descriptions.For the laboratory that has been inactivated with the sampling tube containing guanidine salt, there is no need to inactivate at 56 degrees for 30 minutes.This is only true if non-inactivated sampling tubes are used.

However, I learned from the familiar laboratory leaders that this is not the case. Many laboratories still require samples to be pretreated at 56 degrees for 30 minutes regardless of whether the tubes are inactivated or not. I can understand that they are worried about hospital infection and laboratory exposure. But generally speaking, reducing the false negative rate, increasing the detection amount and taking corresponding measures to control the epidemic situation as soon as possible, I think the corresponding suggestions in the corresponding guidelines are also the best choice from the overall situation and supported by data.

Our laboratory should not control the occurrence of hospital sensation and laboratory exposure at the expense of reducing the detection rate, but should focus on stricter control of experimental steps, more cautious PPE wear and higher laboratory environment.

Solution:

1. It is suggested that the state give special instructions to laboratories at all levels on this matter.

2. It is suggested that the country should further study the preservation solution of sampling tubes, and if there is any preservation solution that can not reduce the detection rate at 56 degrees for 30 minutes, it can also be recommended.

The above zero zero always said a lot of points, mainly about how to reduce false negative conclusions, hoping to give you a reference.

It’s been many days since I wrote this afternoon, mainly considering Spring Festival travel rush. Although the scale of Spring Festival travel rush is reported to have dropped by more than 75% this year compared with previous years, the population flow is still very strong. We may face the rising trend of an epidemic after Spring Festival travel rush, and how to make the work better may be a more urgent need before us.

　　Iranian Foreign Minister Zarif. (Source: Student News Agency)

　　Overseas network September 29 th　Iranian Foreign Minister Zarif said that during his visit to new york, he had a telephone conversation with some members of the US Congress, but unfortunately, he did not hold face-to-face talks with them due to the shortened trip.

　　According to the semi-official Iranian Student News Agency (ISNA) on the 29th, Zarif told reporters when he was preparing to leave new york for Teheran that during his visit, he had talks with different groups in the United States, including some US congressmen. Zarif said that he was called by members of the US Congress. Due to the shortened itinerary, he could not coordinate these members to come to new york for face-to-face talks. He deeply regretted this. Zarif stressed that these US lawmakers have not made any demands on Iran, and Iran will not interfere in the US election. The Iranian side has held talks at the request of the other side and used these talks to show the true image of Iran.

　　Iranian President Rouhani and American President Trump. (overseas network puzzle)

　　When talking about the reports about the meeting between Rouhani and Trump, Zarif said that Trump was only trying to hold talks with Rouhani during his stay in new york this week, and Trump was unwilling to accept the lifting of sanctions as a prerequisite for the talks, so the bilateral talks could not take place. Zarif pointed out that direct talks between Trump and Rouhani have never been put on the agenda, and Iran is only willing to participate in the talks within the framework of the Iranian nuclear deal. Zarif also said that Trump did not promise to lift the sanctions after the talks, but Trump preferred to hold the talks directly and it was possible to lift the sanctions after the talks.

　　The Iranian side’s trip to the United States this time can be described as a thorn all the way. The 74th session of the United Nations General Assembly opened on September 17, 2019. Earlier, Iranian President Rouhani and Foreign Minister Zarif were delayed in obtaining American visas. Rouhani and Zarif "may cancel" their trip "if (the US) doesn’t issue visas within a few hours", Yitong News Agency reported on the 18th. On the same day, Trump said on the Iranian visa issue, "This matter does not depend on me." It was not until 19th that the Iranian delegation to the United Nations announced that the United States issued visas to the Iranian President and Foreign Minister, allowing them to attend the UN General Assembly in new york.

　　Iran said earlier that only when the United States returns to the agreement can the two sides contact. (Photo: Associated Press)

　　On the other hand, the repeated statements of the United States do not rule out the possibility of Trump meeting Rouhani during the UN General Assembly. On the 4th, after imposing additional sanctions on Iran, when asked about the possibility of meeting with Iranian leaders during the UN General Assembly, Trump said that "everything is possible". When he delivered a speech at the UN General Assembly on 24th, Trump also said that the possibility of direct dialogue with Iran was not ruled out, but the sanctions would not be lifted in advance.

　　However, the premise of the Iraqi side is that the United States must lift the sanctions before there can be talks. Iranian Foreign Minister Zarif said on the 22 nd that the premise of holding talks is that Trump promised to ease sanctions against Iran. Iranian President Rouhani also said in his speech at the general debate of the United Nations General Assembly on 25th that Iran has never bowed to foreign forces and refused to negotiate with those who imposed "the harshest sanctions in history". (Compile/Overseas Network Hou Xingchuan)

　　Hubei Daily News (Reporter Wang Jing, arel) On December 30th, Ying Yong, secretary of the provincial party committee, presided over a forum to listen to the opinions and suggestions of grassroots party member cadres, heads of enterprises and universities and representatives of non-party people. Ying Yong stressed that it is necessary to conscientiously study and implement the spirit of the important speech delivered by the Supreme Leader General Secretary at the the Political Bureau of the Central Committee Special Democratic Life Conference, earnestly increase historical self-confidence, promote unity and unity, and enhance the spirit of struggle. Taking this democratic life conference as an important test of adhering to the "two establishments" and "two maintenances", we should further strengthen party leadership and party building, unite the wisdom and strength of the whole province, and provide for accelerating "building a fulcrum, walking in the forefront, and writing a new chapter"

　　At the forum, Huang Keli, secretary of Gucheng County Committee of Xiangyang City; Peng Qiang, secretary of Shengli Town, Luotian County, Huanggang City; Dong Shouzhi, secretary of Xiqiao Community, Tangjiadun Street, Jianghan District, Wuhan City; Wu Jing, secretary and chairman of Hubei Cultural Tourism Group Co., Ltd.; Jiang Liping, chairman of the provincial committee of Taiwan League and president of the provincial Taiwan Federation; Zheng Jun, member of the Central Committee of the Chinese Revolutionary Committee and president of Hubei Second Normal College; and Zhu Mei, full-time vice chairman of the provincial committee of the NLD. Tong Jinnan, member of Chinese People’s Political Consultative Conference and director of the State Key Laboratory of Biogeology and Environmental Geology of China Geo University (Wuhan), put forward opinions and suggestions on accelerating the development of county economy, improving the ability of grassroots cadres, deepening party building to lead grassroots governance, promoting the reform of provincial state-owned enterprises, continuously optimizing the business environment, and strengthening the training and use of non-party cadres. You should listen and take notes, interrupt from time to time, and discuss and communicate with you.

　　After listening carefully to the speech, Ying Yong said that everyone put forward good opinions and suggestions from various fields and aspects in combination with the actual work, which will help the provincial party Committee to grasp the facts, improve its work, better implement the decision-making arrangements of the CPC Central Committee, and help the Standing Committee of the provincial party Committee to hold a special democratic life meeting. We will listen carefully and fully absorb it, and take practical and effective measures to do a good job and promote implementation.

　　Ying Yong pointed out that under the strong leadership of the CPC Central Committee with the Supreme Leader as the core and under the scientific guidance of the Supreme Leader’s Socialism with Chinese characteristics Thought in the new era, Hubei has made decisive achievements in epidemic prevention and control and post-epidemic revitalization. It is a vivid and concrete educational practice for Hubei to hand over the qualified answer sheet for the Great War Examination, which is to strengthen the "four consciousnesses", strengthen the "four self-confidences" and achieve the "two maintenance". It is necessary to profoundly understand the decisive significance and role of the "Two Establishments", and deeply understand that resolutely safeguarding the core of the CPC Central Committee and the core of the whole party is the key to the party’s consensus and decisive choice at major moments, and it is an important guarantee for the party’s unity and victory. Constantly improve political judgment, political understanding and political execution, and always maintain a high degree of consistency with the CPC Central Committee.

　　Ying Yong stressed that it is necessary to thoroughly study and implement the spirit of the Sixth Plenary Session of the 19th CPC Central Committee and the Central Economic Work Conference, hold democratic life meetings with high quality and high standards, further strengthen the party’s political construction, guide the vast number of party member cadres in the province to learn wisdom and strength from the party’s century-long struggle history, vigorously carry forward the great spirit of party building, practice the initial mission, bravely move forward, do good deeds, do their best, effectively deal with the uncertainty of the external environment with the certainty of their own development, and continue to write about the high quality of Hubei’s economy and society.

　　Dong Weimin, member of the Standing Committee of the Provincial Party Committee and Secretary General, attended the forum.

　　September is autumn, the temperature drops gradually, the temperature difference between day and night increases, kindergartens and schools in various places open one after another, the mobility and aggregation of people increase, and the Mid-Autumn Festival holiday and other factors are superimposed, which easily leads to the spread and popularity of many infectious diseases. Henan CDC hereby reminds the general public to pay attention to novel coronavirus infection, whooping cough, norovirus infectious diarrhea, dengue fever, school tuberculosis and food poisoning this month.

　　Key tips

　　1. novel coronavirus infection

　　The epidemic situation of COVID-19 in our province showed a fluctuating upward trend since the end of July, and it showed a fluctuating downward trend after reaching its peak in mid-August. In autumn, students start school one after another, and the Mid-Autumn Festival is approaching, the flow and gathering of people increase, and the risk of infection in COVID-19 increases. In crowded places such as public transportation and shopping malls, we should persist in personal protection to reduce the risk of virus transmission.

　　Protective measures:

　　1. Strengthen the protection of high-risk groups. Targeted measures are taken for high-risk groups such as patients with basic diseases and the elderly, so that cases can be found in time and treated effectively, and serious cases and deaths can be reduced as much as possible. Timely discover and deal with possible cluster epidemics in places where people gather, such as kindergartens, schools and old-age care institutions.

　　2. Pay attention to personal protection. Residents should wear masks in their daily trips, minimize unnecessary gatherings and keep social distance. Maintain good personal and environmental hygiene, wash hands frequently, often ventilate, pay attention to rest, pay attention to nutrition and enhance physical fitness.

　　3. Use drugs rationally and see a doctor as needed. After infection, asymptomatic infected persons and mild cases should take care of themselves at home, reduce contact with their roommates, use symptomatic drugs rationally according to relevant guidelines, do a good job in health monitoring, and go to medical institutions in time if the condition worsens.

　　2, whooping cough

　　Pertussis is an acute respiratory infectious disease caused by Bordetella pertussis, and its typical clinical manifestations are paroxysmal, spasmodic cough and crowing inhalation roar. The disease has a long course and can last for 2-3 months, so it is called "whooping cough". It is mainly transmitted by air droplets, but also by direct contact with respiratory secretions of patients. The population is generally susceptible, and infants without immunization history are at higher risk.

　　Protective measures:

　　1. Standardize vaccination. Vaccination with DTP vaccine can reduce the risk of severe pertussis and death in infants. According to the requirements of the national immunization program for children, school-age children should be vaccinated with DTP vaccine as soon as possible, and school-age children who have not been vaccinated all the time should be replanted as soon as possible.

　　2. Seek medical attention in time. Especially when infants and young children have paroxysmal spastic cough or have their own sudden cough after similar cases around them, they should take the initiative to seek medical treatment in time to reduce the risk of epidemic spread and serious illness.

　　3. Do daily protection. Keep good hygiene habits, wash your hands frequently and ventilate frequently, cover your mouth and nose with elbows or paper towels when coughing or sneezing, and pay attention to reasonable work and rest and proper physical exercise. Try to avoid crowded and poorly ventilated public places.

　　3, norovirus infectious diarrhea

　　Norovirus is a group of non-encapsulated RNA viruses, which has the characteristics of strong infectivity, rapid spread, short immune protection time and general susceptibility of the whole population. It is the most important pathogen that causes acute gastroenteritis. It can be transmitted through polluted water and food, and can also be infected by aerosol inhalation or contact with items contaminated by virus. Shellfish such as oysters and raw fruits and vegetables are common foods that cause infection. It is easy to spread in crowded places such as schools and kindergartens. In the autumn school season, kindergartens, schools and other educational institutions should do daily protection and strengthen health monitoring.

　　Protective measures:

　　1. Maintain personal hygiene. Pay attention to washing hands frequently to prevent diseases from entering the mouth, especially before and after meals and before preparing and processing food.

　　2. Pay attention to the hygiene of diet and drinking water. Do not eat uncooked food and unpasteurized milk, shellfish and seafood such as oysters should be eaten after deep processing; Fruits and vegetables should be carefully washed before eating, and do not eat unclean fruits and vegetables; Separate raw and cooked foods to avoid cross-contamination; Ensure the safety of water sources, do not drink raw water, and the selection of bottled water should meet the hygiene standards.

　　3. Pay attention to standardization. The environment or the surface of an object polluted by the patient’s vomit or excrement should be cleaned and disinfected by trained personnel with chlorine-containing disinfectants or other effective disinfectants. In the process of handling patients’ vomit, excrement and disinfection, you must do personal protection, wear masks and rubber or disposable gloves, and carefully clean and disinfect your hands after cleaning.

　　4. Dengue fever

　　Dengue fever is an acute infectious disease caused by dengue virus. Its clinical manifestations are persistent fever, accompanied by severe headache, myalgia, joint pain, nausea, vomiting and rash. In severe cases, bleeding, shock, organ failure and even death may occur. The disease is mainly transmitted by the bite of Aedes mosquitoes. September is still the peak of mosquito activity, so we should keep good environment and room hygiene in our daily life, reduce mosquito breeding and reduce the risk of infection. At the same time, people who travel and work in dengue epidemic areas should pay attention to personal protection to prevent mosquito bites, and do a good job of self-health monitoring after returning from epidemic areas.

　　Protective measures:

　　1. Do a good job in mosquito control. Clean up the accumulated water in indoor containers such as flowerpots and drinking fountains in time, clean up domestic garbage and sanitary dead corners, and keep the room clean and tidy. Install screen doors and screens in the room, and use mosquito-repellent incense, mosquito killer and electric mosquito swatter to prevent and repel mosquitoes.

　　2. Personal protection should be done when going to dengue epidemic areas. You should wear long-sleeved clothes and trousers, spray repellent and mosquito repellent on bare skin, use mosquito nets when sleeping, and try to choose hotels with air conditioning or screens.

　　3. Do your own health monitoring. After symptoms appear, you should seek medical advice as soon as possible, and actively inform the doctor of the relevant residence history for early detection, early diagnosis and early treatment.

　　4. Use of personal protective equipment. Personal protective equipment such as mosquito nets and mosquito repellent can effectively prevent mosquito bites, thus reducing the probability of dengue virus infection. In areas with frequent mosquito activities, it is recommended to use mosquito nets or apply mosquito repellent to protect yourself.

　　5, school tuberculosis

　　Tuberculosis is a chronic infectious disease caused by Mycobacterium tuberculosis, which can invade many organs, and pulmonary tuberculosis infection is the most common. It is mainly transmitted by respiratory droplets, and healthy people may be infected by inhaling air droplets with tuberculosis. The main symptoms are cough, expectoration lasting for more than 2 weeks, chest tightness, low fever in the afternoon, fatigue, loss of appetite, emaciation, night sweats and so on.

　　Tuberculosis is one of the infectious diseases that schools focus on preventing and controlling. It is the beginning season of autumn recently, and it is a high incidence period of tuberculosis. Schools, parents and students should pay attention to the prevention and control of tuberculosis.

　　Protective measures:

　　1. Strengthen campus management. It is suggested that schools should strengthen the morning check-up, afternoon check-up and late check-up of students in school, implement measures such as tracking students’ absence from class and tracing the cause, and find tuberculosis patients and suspects in school as soon as possible.

　　2. Pay attention to personal protection and improve the body’s immunity. Pay attention to window ventilation, do not spit everywhere, and cover your mouth and nose with your elbow when coughing or sneezing. Reasonable diet, balanced nutrition, combining work and rest, ensuring adequate sleep and appropriate outdoor activities, enhancing physical fitness and improving body resistance.

　　3. Standardize the whole course of treatment. The whole treatment course of pulmonary tuberculosis is 6-8 months, and the whole treatment course of drug-resistant pulmonary tuberculosis is 18-24 months. According to the doctor’s standard treatment, most tuberculosis patients can be cured.

　　6. Food poisoning

　　Food poisoning is a major disease, which is caused by nausea, vomiting, abdominal pain, diarrhea and other symptoms after eating food contaminated by toxic and harmful substances or containing toxins. In September, the high temperature and high humidity weather continued in many places in China, which also created conditions for the proliferation of bacteria. Food is more prone to spoilage. With the large number of seafood on the market, it is necessary to pay attention to the pollution of seafood by Vibrio parahaemolyticus, which is easy to cause food poisoning.

　　Protective measures:

　　1. Pay attention to food hygiene and achieve "six noes": don’t eat uncooked and thoroughly cooked food, unclean fruits and vegetables, food of unknown origin, picking and eating wild mushrooms and wild plants, and don’t buy wild mushrooms picked and sold by individuals, and don’t buy wild mushrooms at mobile stalls.

　　2. When eating out, pay attention to the selection of catering units with complete licenses and good sanitary conditions. Buy food in supermarkets or vegetable markets with health protection.

　　3. Pay attention to personal hand hygiene, wash your hands before and after meals, before and after handling raw and cooked food and its packaging, after touching pets and disposing of garbage.

Xinhua News Agency, Beijing, September 2ndQuestion: How to upgrade consumers’ enjoyment of trade-in support of overweight in various places?

Xinhua News Agency reporters Xie Xiyao, Li Xiaoting and Gong Liankang.

Recently, the "upgraded version" policy of promoting the trade-in of automobiles and home appliances at the central level has been introduced one after another. The reporter recently visited markets in Beijing, Hubei, Chongqing, Fujian and other places, and learned that all localities have introduced detailed rules for the replacement of old consumer goods in light of local actual conditions, expanded the coverage of subsidized products, upgraded subsidies, made the application process more convenient, and increased consumers’ willingness to purchase.

Government subsidies are superimposed on enterprises to make profits, and new subsidies for automobile replacement and renewal are added.

On the evening of August 27th, the reporter went to the Geely Yinhe Wuhan Star Experience Center in Hanyang District, Wuhan. The slogan of "trade-in" subsidy for cars in the store was everywhere, and many citizens went to the store to see cars and consult preferential policies.

The salesperson took the store’s best-selling model Geely Yinhe E8 as an example and calculated a "detailed account" for the reporter:

For a new car with an original price of 165,800 yuan, if the customer’s old car meets the scrapping conditions, the maximum state subsidy can be 20,000 yuan; Or transfer the car under his name, you can get a replacement subsidy of 12,000 yuan. During this period, you can also apply for a trade-in coupon of up to 2,000 yuan in Wuhan at the same time, plus a discount of more than 10,000 yuan from manufacturers and 4S stores, and the maximum superimposed discount for buying this new car can reach more than 30,000 yuan.

According to the national policy, for individual consumers who meet the provisions of the Detailed Rules for the Implementation of Vehicle Trade-in Subsidies and scrap old cars and buy new ones, the subsidy standard will be increased from 10,000 yuan for new energy passenger cars and 7,000 yuan for fuel passenger cars to 20,000 yuan and 15,000 yuan respectively. In addition to scrapping and updating, this policy will also include replacement and updating in the scope of subsidies, and support local governments to carry out replacement and updating independently.

At present, following the rhythm of national policies, local governments have successively launched trade-in schemes focusing on the local automobile market.

The national dicing and matching funds in Hubei Province are more than six times the size of the funds before the afterburner measures. The maximum subsidy for car scrapping and renewal is 20,000 yuan, and the maximum subsidy for replacement and renewal is 16,000 yuan.

Beijing has made it clear that the newly purchased new energy vehicles after replacement include not only pure electric vehicles, but also plug-in hybrid vehicles (including extended-range vehicles) and fuel cell vehicles, and all of them can enjoy replacement subsidies if they are transferred inside and outside Beijing.

Shanghai puts used cars in an important position in the trade-in policy, encourages the development of used car distribution business, and makes it clear that the average age of used cars will be reduced by one year by 2027 …

Government subsidies are superimposed on enterprises to make profits, new replacement and renewal subsidies are added, and consumers’ willingness to buy new cars is increased.

Up to now, the trade-in of consumer goods in Hubei has benefited more than 400,000 consumers, driving the sales of new cars and home appliances to 12 billion yuan. Wuhan has achieved the goal of trade-in of automobiles for the whole year ahead of schedule; As of mid-July, Hunan has received more than 8,600 applications for automobile scrapping and renewal subsidies, and more than 23,000 applications for replacement and renewal subsidies, which has driven automobile sales to exceed 5.5 billion yuan. From the release of the National New Deal to September 1st, the cumulative amount of old-for-new subsidies in Chongqing reached 9,748, and the cumulative sales of automobiles exceeded 1.837 billion yuan.

According to the data of the Ministry of Commerce, as of 10: 00 a.m. on September 1, more than 810,000 applications for car scrapping and renewal subsidies were received. From January to July, the national automobile retail sales reached 11.556 million, up 2.3% year-on-year. Among them, the retail sales of new energy passenger cars was 4.988 million, a year-on-year increase of 33.7%; The number of used cars was 10.992 million, a year-on-year increase of 6.3%.

The subsidy for home appliance replacement will be expanded, and the on-site application will be reduced immediately.

Mr. Zhou of Nanchuan District, Chongqing recently bought a Haier Class 1 energy-efficient air conditioner with a price of 2,499 yuan and enjoyed a government subsidy of 499.8 yuan for trade-in. "Government subsidies are very cost-effective, and it is very convenient to apply for money immediately." Mr. Zhou said.

On August 26th, Chongqing’s "upgraded version" green smart home appliances trade-in subsidy policy landed. On the first day of the implementation of the policy, the city issued a government subsidy of 8.165 million yuan, which directly led to the sales of home appliances of 42.6335 million yuan.

The reporter learned from the Chongqing Municipal Commission of Commerce that at present, the state’s pre-allocated funds to support trade-in have been issued to Chongqing, and the local governments will match the funds in proportion to jointly promote the trade-in of consumer goods.

The state has made it clear that eight types of household appliances enjoy a subsidy standard of 15% to 20% of the sales price, with a maximum subsidy of 2,000 yuan per piece. At the same time, support local governments to independently determine the varieties of subsidized "8+N" household appliances. Up to now, many places have successively issued implementation rules for the implementation of home appliance trade-in.

Chongqing has made it clear that individual consumers will enjoy 15% to 20% of the sales price of each type of household appliances when they purchase 11 types of household appliances with energy efficiency or water efficiency standards of Grade 2 or above; In terms of superimposed subsidies for enterprises, consumers can enjoy a 2% trade-in subsidy if they sell nine categories of old household appliances and buy any kind of products with energy efficiency or water efficiency of Grade 2 or above.

Beijing consumers can access the "Jingtong" applet through Alipay, WeChat, Baidu, Meituan and other channels, and receive the subsidy qualification codes of more than 10,000 household appliances in 8 categories, and enjoy preferential treatment in the payment link.

On the basis of eight types of household appliances, Guangdong has added three types of products, such as mobile phones, tablets and smart wearable devices, as well as other N-type products that are actually included in the scope of subsidies in various cities, forming an "8+3+N" product category.

From the central government to the local government, the subsidy policy has clearly defined the energy efficiency standards, and only subsidizes energy efficiency products of Grade 2 and above. "Trade-in is not a simple replacement of similar products, but a demand that tends to be higher-end, smarter, more environmentally friendly and more personalized, and supports the transformation and upgrading of household consumption through trade-in." Chen Yaoting, a professor at the Business School of Minnan Normal University, said.

Continue to open up new blocking points and smooth the resource circulation chain.

Recycling has always been a blocking point that affects trade-in consumption, and it is also the key to smooth the recycling of resources.

Fujian Quantong Resource Recycling Industrial Park, located in Zhangzhou Development Zone, Fujian Province, has a truckload of used household appliances entering the factory, weighing, unloading, acceptance, bar coding and warehousing, and then entering the dismantling process. Every day, about 2000 sets of waste household appliances are treated here in a standardized way.

Driven by the trade-in policy, Quantong has established strategic cooperation with recycling enterprises under Midea Group to realize the recycling system of products from sales, recycling to standardized dismantling.

The national policy is clear, all localities should strengthen the construction of digital platforms, learn from each other’s experience, strengthen data analysis, and timely and accurately grasp the information of the whole process of home appliances replacement, purchase and disassembly. The reporter visited and learned that under the guidance of the trade-in policy, the diversified recycling pattern of used household appliances is accelerating.

"Old household appliances are not limited to brands and years, and they can provide one-stop trade-in services such as free door-to-door dismantling of old machines and free transportation." He Yuanlin, general manager of Dahai Daming Trading Co., Ltd., a distributor of Haier Zhangzhou, said that the company is docking with dismantling enterprises with relevant qualifications, establishing a standardized recycling system for used household appliances, and at the same time promoting the development of community services for household appliances.

On September 2, Haier Zhijia Recycling Interconnection Factory was completed and put into operation in Laixi, Qingdao, with an annual dismantling capacity of 3 million units. Shijiazhuang city has perfected the comprehensive utilization system of renewable resources by the mode of "government+property+third party"; Hunan will include the recycling outlets of renewable resources such as waste household appliances into the construction of a convenient living circle for a quarter of an hour; Gree, Changhong and other home appliance companies actively adopt the "internet plus Recycling" method to provide professional old machine recycling services …

Insiders pointed out that with the increase in the number of places to promote the implementation of the old-for-new policy, it will drive the government, enterprises, platforms and other forces to join the field of recycling, and work together to improve the construction of the recycling network of used household appliances, so that consumers are "easier to get rid of the old and more willing to get new ones".

The 14th Press Conference on Epidemic Prevention and Control in COVID-19, Hainan Province.
(February 19, 2020)

Ru Yingying:

Hello, ladies and gentlemen! At present, the epidemic prevention and control work has reached a very critical period. In order to further strengthen the popularization of protection knowledge and ensure the safety of those who return to work and resume production, the Information Office of Hainan Province held the 14th news conference on the epidemic prevention and control work in COVID-19, Hainan Province, and invited Mr. Sun Shaoke, deputy director of the Provincial Big Data Administration, Mr. Chen Jianhong, spokesman of the Provincial Health and Wellness Committee, and Mr. Jin Yuming and Mr. He Bin, chief physicians of the Provincial Center for Disease Control and Prevention, to answer your questions around the theme of "knowledge of epidemic prevention and control in different industries and populations".

First of all, please ask Chen Jianhong, spokesman of the Provincial Health and Wellness Committee, to report the latest epidemic situation.

Chen Jianhong:

First, the latest epidemic situation

From 00: 00 to 12: 00 on February 19th, 2020, novel coronavirus was reported by Hainan Province, and there were no newly confirmed cases, severe cases, deaths and discharged cases.

By 12: 00 on February 19th, Hainan Province had reported 163 confirmed cases, 9 severe cases, 4 deaths and 79 discharged cases in novel coronavirus. Among the confirmed cases, there are 34 cases in Haikou, 54 cases in Sanya, 15 cases in Danzhou, 3 cases in Wenchang, 6 cases in qionghai city, 13 cases in Wanning, 3 cases in Dongfang, 9 cases in Chengmai, 6 cases in Lingao, 7 cases in Changjiang, 4 cases in Lingshui, 3 cases in Ding ‘an, 3 cases in Baoting, 2 cases in Ledong and 1 case in Qiongzhong.

By 12: 00 on February 19th, 5,280 close contacts had been tracked, 4,196 people had been released from medical observation, and 1,084 people were still under centralized medical observation.

Second, the daily epidemiological risk warning (February 19)

In recent years, the number of newly diagnosed cases in our province has remained low continuously, and the number of discharged cases has increased significantly. However, due to the recent resumption of work and other factors, if the prevention and control measures are not in place, there may be epidemic fluctuations in the future. The prevention and control suggestions are as follows:

1 prevention and control departments at all levels should strengthen the epidemic monitoring and related prevention and control measures after the resumption of work. In particular, key areas such as Haikou and Sanya should strengthen prevention and control.

2. Try to go to work at the wrong time, arrange shifts flexibly, prohibit gatherings and dinners, implement a meal sharing system, clean up the working and living environment, reduce the living density and strengthen ventilation.

Ru Yingying:Next, please answer the questions that journalists and netizens care about.

Q:Our province launched the health code system on February 18th. Could you tell us something about it?

Sun Shaoke:

Thank you for your question. I will break your question down into twelve sub-questions to answer.

(1) What is Hainan Health Code?

Hainan Health One Code System is a personal two-dimensional code generated by comparing and verifying the health data declared by residents or people returning to work, combined with epidemic prevention big data information.

(2) What is the meaning of "three colors" of Hainan health code?

A green code indicates that there are no symptoms at present. According to local management requirements, you can check the bright code of body temperature. The yellow code and the red code do not meet the traffic conditions for epidemic control, and they can travel normally only after being converted into green codes.

(3) What are the differences between the green code, the yellow code and the red code?

Health codes are divided into three colors: red, yellow, green, yellow and red.

1. When the access control at the bayonet or the enterprise returns to work, the green code personnel can pass by the code and go to work normally. Those who receive the red code and the yellow code need to be isolated according to the regulations and make a daily health punch card. When the conditions are met, they will be turned into green codes.

2. In principle, the "red code" personnel who entered Qiong shall be advised to return or delayed to Qiong. "Yellow code" personnel shall be observed at home or in centralized isolation according to regulations. Display "green code", and pass the release after bright code and temperature measurement.

(4) How to apply for a green health code?

Users don’t have a health code by default. Please apply for it through government service APP, government big data WeChat official account, Coconut City Minyun, Alipay and WeChat scan code, and punch in your daily health card. The system will automatically assign you a health code of corresponding color according to your health information.

(5) How can the red code/yellow code be converted into green code?

Code red and code yellow personnel must punch in the registration information for 14 consecutive days and meet the relevant conditions before they can turn into green codes.

(6) What are the functions and functions of Hainan health code?

Hainan health code can be applied and popularized in multiple scenarios, which can improve work efficiency and control quality. In management scenarios such as grid worker’s door-to-door inspection, community gate inspection, unit enterprise’s return to work registration, road traffic checkpoint inspection, fever clinic, fever medicine purchase, etc., people’s personal health code can be directly scanned, information can be collected without contact, reporting is convenient, and data can be shared and utilized, which is conducive to rapid epidemic prevention work.

(seven) the scope of application of Hainan health code?

Hainan health code is applicable to those who are in Hainan and those who are waiting to enter Hainan.

(eight) Hainan health code which occasions need to be used?

During the epidemic prevention and control period, the health code can be used as an electronic passport for work, study and life in Joan. Please take the initiative to show it to cooperate with the inspection when necessary. In addition, the health code can also be used in scenes such as hospitals, pharmacies and enterprises returning to work and production.

(9) What is the significance of Hainan health code for enterprises to resume work and production?

Grasp the real-time health status of employees through employee health codes, effectively arrange work for different people, and reduce the risk of epidemic spread caused by gathering; At the same time, it is also conducive to effectively evaluating the risk of enterprises’ resumption of production and work, better balancing the relationship between epidemic prevention and control and enterprises’ resumption of production through health code, and promoting the orderly development of social economy.

(10) Where can I register to check the health code?

The health code system has been provided in platforms such as Hainan Government Service APP, Hainan Government Big Data WeChat official account, Coconut City Minyun, Alipay, etc. Citizens can scan the code and log in through Alipay, Coconut City Minyun APP, WeChat, mobile browser and other channels.

(11) Can health codes only be used by Hainan natives? Can I use it from other places?

The health registration function is used for personal self-help online health status report. No matter local residents, people who have returned to Qionglai from other provinces or Hubei Province, they can register their own health by punching in the health registration function of the health code.

(12) How to consult if there are problems in the use of health codes?

Members of the public can call the Hainan 12345 government service hotline to ask questions related to health codes.

Q:Yesterday, our province issued "Ten Measures for Migrant Workers to Work in Provincial Key Projects and Key Projects during the Epidemic Prevention and Control Period", and construction sites in our province will start one after another. How to do a good job in epidemic prevention and control after the construction sites resume work?

He Bin:

After the construction site resumes work, all parties involved in the construction should implement the main responsibility of prevention and control, strictly do a good job in epidemic prevention and control, and file a record for future reference.

(1) Personnel control requirements.

1, completes the personnel registration;

2, do a good job in all field personnel temperature detection;

3. Do a good job in reporting the causes of absenteeism;

4. Make emergency response.

(2) Requirements for control on the construction site.

1. The construction enterprise shall set up temperature detection points at the entrance and exit of the construction site, and all personnel must have temperature detection when entering the construction site. Persons with body temperature greater than or equal to 37.3℃ should be sent to the isolation observation dormitory in time for further isolation observation. After resting in the isolation observation dormitory for 10 minutes, if the body temperature is still greater than or equal to 37.3℃, appropriate protective measures should be taken and sent to the fever clinic designated by the health department in time. All personnel entering the site should wear masks and take personal protective measures. Decentralize pre-shift education, technical disclosure and other activities to reduce personnel gathering and meetings.

2. According to the relevant technical requirements, carry out ventilation, disinfection and epidemic prevention work on the construction site, office and living areas (site canteens, dormitories, toilets and other places) and other personnel activities.

3, strict implementation of food procurement, processing, storage and other health standards, not illegal slaughter, disposal of wild animals, and effectively protect food safety. The canteen on the construction site can take measures such as separate meals and wrong meals, and it is forbidden for people to have dinner.

4, do a good job in the classification of domestic waste, in strict accordance with the requirements of the disposal of discarded masks and other medical protective equipment waste.

5, the construction site should be related to health and epidemic prevention education into the approach and daily pre-job education, fully launch the publicity and education of novel coronavirus related knowledge, take measures such as posting health and epidemic prevention advertisements in a prominent position in the construction site and living quarters, and improve the prevention and control awareness of field personnel.

6, the implementation of epidemic prevention and control work to implement the daily system and emergency reporting system.

Q:How do migrant workers and other migrant workers do personal protection?

He Bin:

(a) before returning to the city, to carry out temperature measurement, to ensure that there is no abnormal increase in body temperature.

(2) Measure your body temperature before going to work every day on weekdays and make records. If you have symptoms such as fever and cough, you should be isolated in time and seek medical treatment.

(three) when many people work together in the workplace, each person should wear a mask.

(4) Wear masks on the way to the workplace, and keep a certain distance between people.

(five) collective dormitory ventilation frequently, the distance between beds is more than 1 meter, daily cleaning, timely cleaning of garbage, and thorough cleaning and cleaning of the dormitory every week.

(6) Take meals at the wrong time to avoid dinner. Clean the restaurant thoroughly after each meal, with no food residue on the dining table and no sanitary corner on the ground, and remove the kitchen garbage in time. Clean and disinfect the used tableware in time.

(seven) keep the public toilet ventilated. Sanitary cleaning shall be carried out at any time every day, and the floor and walls shall be kept clean. There shall be no dirt in the sink and no feces and dirt accumulation in the urinal. Disinfect urinals every day.

(eight) wear a mask when traveling daily, and do not litter or spit when going out. When sneezing, cover your nose and mouth with paper towels, or use elbows and arms to keep a certain distance from others, and do not move in crowded places. Do a good job of hand hygiene after going out and returning.

Q:How to prevent and control the epidemic situation in the collective office after returning to work?

Jin Yuming:

(a) staff should do a good job of health monitoring, if there are suspicious symptoms of novel coronavirus infection (including fever, cough, sore throat, chest tightness, dyspnea, fatigue, nausea and vomiting, diarrhea, conjunctivitis, muscle aches, etc.), don’t go to work sick, you should report to the unit in time and go to the fever clinic for investigation.

(2) If suspicious symptoms of novel coronavirus infection are found, the staff should register and ask them to go to the nearest fever clinic for investigation.

(three) public goods and public contact items or parts should be cleaned and disinfected regularly.

(four) to maintain air circulation in the office. Ensure the normal operation of the air conditioning system or exhaust fan, clean the air conditioning filter regularly, and strengthen the ventilation by opening the window.

(five) the bathroom should be equipped with enough hand sanitizer to ensure the normal work of water supply facilities such as faucets.

(six) keep the environment clean, clean up the garbage in time.

Q:How do students protect themselves during the winter vacation and on the way back to school?

Jin Yuming:

(1) During the winter vacation.

1. Students who have a history of residence or travel in epidemic-prone areas (such as Wuhan) have been under medical observation at home or in designated places for 14 days since leaving the epidemic-prone areas.

2. Students from all over the country should stay at home as much as possible, reducing visits to relatives and friends, gatherings and dinners, and activities in crowded public places, especially in places with poor air mobility.

3. Students are advised to monitor their health every day and report to the designated person in charge of the community or school as required.

4. At the end of the winter vacation, students can return to school normally if they have no suspicious symptoms. If you have any suspicious symptoms, you should report them to the school or the guardian, and seek medical treatment in time, and then go back to school after recovery.

(2) On the way back to school

1. Wear medical surgical masks all the time when taking public transport.

2, keep hand hygiene at any time, reduce contact with tools of public goods and parts.

3. Do a good job in health monitoring during the trip, and take the initiative to measure your body temperature when you feel feverish.

4. Pay attention to the health status of the surrounding passengers and avoid close contact with people with suspicious symptoms.

5. If there are suspicious symptoms during the trip, you should take the initiative to put on a medical surgical mask, try to avoid contact with other people, and seek medical attention in time according to your condition.

6. If you need to see a doctor in a medical institution during the trip, you should take the initiative to tell the doctor about the travel and residence history of the relevant disease-endemic areas and cooperate with the doctor to carry out relevant investigations.

7. Keep the travel ticket information properly to cooperate with the investigation of possible close contacts.

Q:What are the suggestions for kindergartens (or schools) to prepare for returning to school after the outbreak?

Jin Yuming:

(1) Students who have lived or traveled in areas with high epidemic rates (such as Wuhan) before returning to school are advised to stay at home for 14 days before returning to school.

(2) Students should monitor their body temperature and health status every day after returning to school, try to reduce unnecessary going out and avoid contact with other people.

(3) When students are in close contact with other teachers and students, they should wear medical surgical masks correctly to minimize the scope of activities.

(IV) Schools should closely monitor students’ health status, measure their body temperature twice a day, and make records of absence, leaving early and taking leave. If suspicious symptoms are found among students, they should immediately report to the epidemic management personnel, and cooperate with medical and health institutions to do a good job in the management and disinfection of close contacts.

(5) Schools should try to avoid organizing large-scale collective activities. In classrooms, dormitories, libraries, activity centers, canteens, auditoriums, teachers’ offices, toilets and other activity areas, it is recommended to strengthen ventilation and cleaning, and equip them with hand sanitizers and hand disinfectants.

(six) the school to carry out online teaching, make-up classes for students who missed classes due to illness, for those who delayed the exam due to illness, make-up exams should be arranged and should not be recorded in the file.

Q:At present, farmers’ markets in our province have also resumed business one after another. How can farmers’ markets do a good job in epidemic prevention and control?

He Bin:

(a) the management department of farmers’ market should attach great importance to the prevention and control of epidemic situation, establish the working mechanism of epidemic situation prevention and control, formulate the prevention and control plan, refine the prevention and control measures, implement the prevention and control personnel, put the responsibilities in place, and divide the work among people.

(two) the management department of the farmer’s market should grasp the out-going situation and health status of all operators and relevant staff in the market 14 days before rework. People from high-incidence areas (such as villages, communities and streets with confirmed cases in Hubei Province) must be observed in isolation for 14 days before they can start business and rework. Other migrant workers who have passed the temperature and health examination can do business and rework.

(three) operators and staff in the market daily health monitoring, the establishment of body temperature monitoring register. Operators should maintain personal hygiene when providing services, wash their hands frequently and wear masks all the time.

(4) Strictly implement the system of inspection and acceptance of incoming goods and claiming tickets and certificates. Operators in farmers’ markets shall not purchase food and food raw materials that have no source or do not meet the requirements, and it is strictly forbidden to purchase and use meat and its products that have died of illness or the cause of death is unknown, and that have failed quarantine; It is forbidden to slaughter live livestock and poultry in captivity, to trade live poultry, to purchase and sell wild animals and their products.

(5) Market operators should carry out a general cleaning after the daily closing of their stalls, and clean the countertops, floors, sewers and storefronts with water to keep the stalls clean and tidy, so as to ensure that no sanitary corner is formed. Regularly spray and disinfect sewers, floors around stores, countertops, appliances and chopping boards. When cleaning and disinfecting, wear long water shoes, masks and waterproof gloves, and do a good job in personal hygiene protection. Pay attention to the ventilation of the place (mechanical ventilation is used when necessary). Public toilets should be kept clean and equipped with soap, hand sanitizer or alcohol-containing hand sanitizer to ensure the normal use of water supply facilities such as faucets. Strengthen garbage classification management, set up garbage bins with discarded masks, remove garbage in time, and keep the environment clean and hygienic.

(6) Do a good job in rodent control and pest control. Strengthen the management of garbage in farmers’ markets, require garbage transport vehicles and hand-propelled garbage collection vehicles to be stored and transported in a closed manner, and improve the level of garbage collection, transportation and treatment; Install anti-rat, anti-mosquito and anti-fly facilities. Ensure that the control level of rats, mosquitoes, flies and cockroaches (vectors) in the market meets the requirements of national standards.

(seven) the entrance of the farmer’s market to test the temperature of customers, if necessary, to re-test, to remind passengers to wear masks. People with fever reaching or exceeding 37.3℃ are not allowed to enter.

Q:How to ensure epidemic prevention and production and life in rural areas?

He Bin:

(a) have been to Hubei, relatives and friends from Hubei should promptly inform the village committee, family members, relatives and friends or their own fever, cough, chest tightness and other unwell symptoms, to report early, timely diagnosis and treatment. Wear a mask when going to crowded places, and wear a mask when coughing or having a fever. This is the simplest and most effective protective measure.

(two) clean up the sanitary corner, timely removal of garbage, do a good job in environmental sanitation, prevent mosquito and fly diseases. Do not spit everywhere, cover your nose and mouth with paper towels when coughing or sneezing, and wash your hands after handling.

(3) Wash your hands with soap or hand sanitizer for at least 15 seconds after coughing or sneezing, preparing food, defecating before and after meals, touching animals or handling animal droppings, and going out and returning home, paying attention to scrubbing every part in place.

(4) Open the doors and windows regularly to keep the air circulating at home. Exercise more, drink more water, get enough sleep, mix food with meat and vegetables, separate raw food from cooked food, and try to improve your immunity.

(five) livestock and poultry should be kept in captivity, cleaned and disinfected, and vaccinated in time. Do not hunt, kill, process, sell or eat wild animals and their products.

(six) support the work of township and village cadres, and cooperate with the registration and verification of epidemic prevention. Poverty alleviation cadres in the province, especially those at the grassroots level, should guide and help the poor to implement prevention and control measures to ensure that no one is left behind.

(7) Crowd gathering places are risky, so it is necessary to visit relatives and friends less, gather for dinner less, go to markets less, and go to crowded places less. Don’t attend village temple fairs, public meetings, etc.

(eight) if the body is abnormal or in close contact with the confirmed sick person, don’t hide it for fear of isolation. As long as the patients are found and isolated in time, the epidemic situation can be contained quickly. Don’t panic too much and don’t believe in rumors.

(nine) to develop good hygiene habits, don’t litter, especially the worn masks and related protective equipment. If it is possible, it should be centralized and harmless, and if it can’t be centralized, it should be burned by itself.

(ten) don’t refuse to check the temperature of the temporary epidemic prevention checkpoint. In response to the government’s call, migrant workers returned to the city in an orderly manner as required. Migrant workers should not bring live birds and other animals when they return to the city.

(eleven) the plan of the year lies in the spring, the epidemic situation should be prevented, and the production should not stop. We should do a good job in spring field management, spring ploughing and animal husbandry production.

Q:Can I order takeout during epidemic prevention?

Jin Yuming:

It is suggested that the take-away restaurant will distribute the containers containing food outside, and increase the frequency on the basis of the usual cleaning and disinfection requirements to disinfect the delivery staff’s vehicles. Do a good job of cleaning, disinfection and protection, and the possibility of virus transmission through take-away is relatively low. Be sure to wear a mask when taking takeout. It is suggested to carry out non-contact delivery, and inform the delivery staff to put the goods at the designated place, without the need for both parties to sign face to face. When taking takeout, you can bring disposable gloves, or use paper towels to separate your hands from the packaging bag. After taking the takeaway, you can remove the layers of packaging under the protection of gloves or paper towels and throw them into the trash can. Then use the soapbox flowing water to absorb it at the first time, or use antibacterial hand gel containing alcohol to clean your hands. However, we still suggest cooking by yourself and bringing meals. If you go to a restaurant or order takeout, it is recommended to order hot food instead of cold food; If possible, reheat the food before eating to ensure it is cooked thoroughly; Always remember to maintain hand hygiene, wash your hands before and after meals and after touching easily contaminated items.

Ru Yingying:thank you This concludes today’s press conference.

　　(Declaration: The publication of the manuscript of China Newsweek must be authorized in writing)

　　　 Hong Kong Book Fair: A Carnival for Common People to Read.

　　The special status of Hong Kong has made the sales characteristics of Hong Kong’s book industry, which can’t be copied by mainland or overseas book industry.

　　Our reporter/Chen Xiaoping

　　On July 21st, when Typhoon No.3 "Candu" formed in the South China Sea, the 21st Hong Kong Book Fair, which lasted for one week, kicked off at the Hong Kong Convention and Exhibition Center in Victoria Harbour. The coming typhoon has not stopped Hong Kong people’s great enthusiasm for participation. On the overpass leading to the Convention and Exhibition Center in Central Square, Hong Kong people who came to buy books with carts and suitcases jostled each other. Security guards need to take measures to restrict the release, so as to control the flow of people at any time and maintain order.

　　From the 200,000-person attendance of the first book fair in 1990 to the 920,000-person attendance this year, the annual attendance of the Hong Kong Book Fair has been hitting a new high-today, almost one in every seven Hong Kong people goes to the book fair-although this has made the Hong Kong Book Fair a "fair" for books. The Hong Kong Trade Development Council has made this book business stronger and stronger, and such a lively scene is unmatched by Beijing, Shanghai and Chengdu book fairs.

　　Visit book fairs and buy books once a year.

　　From the Wan Chai subway station to the Convention and Exhibition Center, there are all kinds of publishers’ advertisements, book exhibition posters and flags. At the entrance to the venue, people have to wait for the people in front to fully enter the exhibition before releasing the next batch of visitors. It is said that the longest time, the queue was one kilometer, and citizens had to wait for more than 40 minutes to enter the venue.

　　"I really don’t know what supports the enthusiasm of Hong Kong people to visit the book fair," said a Beijing reporter who participated in the Hong Kong book fair for the first time. Seeing such a scene makes people dizzy, and if the goal of buying books is not clear, it is very painful to find a book in the book fair, just like looking for a needle in a haystack.

　　Including Chinese and English booksellers (bookstores) across the Taiwan Strait and three places, as well as foreign language books from many countries, all publishing houses and bookstores directly enter the venue to set up booths to sell books. Just like the temple fair in Beijing, there are constant shouting and selling in the venue, and there are even booths selling books with banners of "20% off for one book, 30% off for six books and 6.5% off for ten books".

　　On the 22nd, the second day of the book fair, the storm, accompanied by lightning, did not stop Hong Kong people from buying books at the book fair. From time to time, I see book buyers with suitcases, and most of them are mainstream bestsellers. Teenagers prefer "light novels", while the elderly prefer health books. The so-called "light novel" refers to the combination of novels and cartoons. It is a kind of entertaining literary book, which tells stories with cartoons, pays attention to pictures and has shots, and is mostly imported from Japan.

　　During the summer vacation, the main force during the day is middle school students, and some "light novels" are even sold in bundles. In the evening, the age of book buyers goes up. After dinner on Friday, office workers become the main force of the book fair. On the weekend, married with children’s parent-child group appears at the book fair, and Hong Kong people enjoy the seven-day book carnival as a holiday.

　　It has been 21 years since the Hong Kong Book Fair. Visiting the book fair in these seven days has become an annual habit of Hong Kong people. Many young people don’t usually visit bookstores to buy books. They will save a sum of money to buy books at the annual book fair, and even compare with friends.

　　For this phenomenon, Ma Jiahui, a Hong Kong cultural person, explained: "This is a tragedy in Hong Kong. In Hong Kong, there is not even a decent bookstore, and the usual pace of life is very tight. Ordinary people read and buy books less frequently."

　　Hong Kong people advocate fast food culture, and newspapers and periodicals are the main reading contents of the citizens. Young people in Hong Kong usually don’t like reading, and they are not encouraged to read. They don’t know which bookstore to buy books. Therefore, as Ma Jiahui said, if there is no book fair, young people in Hong Kong may not buy books 365 days a year.

　　Hong Kong Commercial Press is a publishing house with the largest retail bookstore in Hong Kong. It has 21 bookstores in Hong Kong and Macao, and also has a professional English law bookstore. The annual turnover of the whole bookstore is 600 million Hong Kong dollars. However, in charge of such a leading enterprise in the book industry in Hong Kong, managing director Lu Guo also lamented that the book market was difficult to do. Although the flagship store of Hong Kong Commercial Press in Tsim Sha Tsui is one of the bookstores that mainland scholars like to visit in Hong Kong, the bookstore has suffered the fate of moving three times in five years because of the high rent and the owner’s failure to renew the contract.

　　Ma Jiahui said that Hong Kong bookstores were all killed by real estate developers.

　　Readers inside and outside the book fair

　　In February, 1923, Sun Yat-sen gave a speech at the University of Hong Kong, saying that his thought originated in Hong Kong. But four years later, when Lu Xun went to Hong Kong to give a speech, a group of literary youths complained to Lu Xun that Hong Kong was a "desert area" ideologically, and the statement that Hong Kong was a "cultural desert" was widely spread.

　　All along, the Hong Kong Trade Development Council has been organizing book fairs with the idea and concept of business management. From asking stars to take the lead in reading and writing books as a marketing tool, to "the second kind of books and periodicals" with pornographic and violent content becoming the focus of the book fair, and then to the invasion of the tender model photo album into the book fair, which also makes the negative news about the book fair continue every year, and the book fair also expands constantly every year, with the increase of exhibition halls, booths and sales figures of books.

　　In 2005, Fred Lam, the new president of the Hong Kong Trade Development Council, proposed that the Hong Kong Book Fair should pay equal attention to culture and commerce. Fred Lam suggested that the TDC is a commercial organization, not a cultural organization, and it is not good at doing cultural things. "We should find excellent cultural institutions and groups in Hong Kong to do this.". Later, they hired the Hong Kong Arts Development Council, Ming Pao Group, Asia Weekly and other cultural organizations as staff officers, and finally decided to cooperate with Asia Weekly to invite writers and cultural celebrities from three places across the Taiwan Straits to give lectures at the book fair.

　　This year’s book fair also opened the "Hong Kong Writers’ Tour 2010" exhibition area for the first time to promote outstanding local writers in Hong Kong, and followed the example of Frankfurt Book Fair to join the works recitation.

　　This year’s book fair invited more than 90 writers to participate in more than 270 cultural and outreach activities. Among them, invited lecturers from the Mainland include Feng Jicai, He Weifang, Pan Shiyi, Zhang Yihe and Han Han. In addition, the speakers of the "Famous Lectures" include Zhou Guangqian, Ge Liang and Lin Peili from Hongkong, Chen Wenxi, Liu Kexiang, Lan Bozhou and Tang Nuo from Taiwan Province, jade y. chen living in Germany and Du Weiming from the United States.

　　In a lecture hall with less than 200 people, Liang Wendao, a Hong Kong writer, is sharing his creative experience with readers. The audience included old people with white hair, peers from Liang Wendao, and more young people, many of whom came from Guangdong to attend the Hong Kong Book Fair.

　　A local young man in Hong Kong, wearing glasses, T-shirt shorts and a pair of straw flip-flops on his feet, listened carefully and took notes on a single piece of paper. It can be seen that young people like Liang Wendao very much, and listen to the lectures carefully.

　　Liang Wendao said that the characteristic of Hong Kong writers is to do their own things silently and write their own books. It seems that the readers in Hong Kong are the same.

　　But more readers are actually outside the book fair. "I haven’t been to the book fair for a long time. My writing doesn’t need to deal with modern people, but is related to the dead." On the other end of the phone, Huang Canran, a Hong Kong poet and translator, told China Newsweek. He goes to work at five o’clock every afternoon and writes in the early hours of the morning. For him, in this busy morning, the day has just ended.

　　In Hongkong, there is also a group of English-reading people. No one has counted the size of this group, but Ma Jiahui told a story: once he made an appointment for a book review and introduced the Chinese version of Said’s books on music. Later, his friend in the Hong Kong Commercial Press told him that the bookstore kept the original English version of the book for one year and hardly sold a few copies. However, after the book review, the original English version sold 20 copies within a week, while the Chinese translation only sold a few more.

　　Hong Kong books export to domestic market.

　　Since 2003, when the mainland opened free travel for tourists to visit Hong Kong, the Hong Kong Book Fair began to welcome mainland readers. Subsequently, the Hong Kong Book Fair set up a "visiting channel", through which you can get preferential ticket purchase. Through these measures, the organizers attract mainland readers to buy books in Hong Kong. According to the statistics of the Hong Kong Trade Development Council, the number of people who entered the 20th Hong Kong Book Fair through the "visiting channel" reached 10,000 last year, and the organizers thought that a considerable number of mainland tourists should follow Hong Kong friends or queue up for admission. In fact, the number of people from the mainland who went to the Hong Kong Book Fair was far more than that.

　　"Export to domestic market" is one of the characteristics of Hong Kong books. Most of the authors of Chinese works in Hong Kong, especially academic works, come from mainland scholars, and these academic works have returned to the mainland, which has formed a big market, except for local and overseas research institutions. Scholars’ "export" and works’ "domestic sales" are an intriguing structure of the Hong Kong book market.

　　The Chinese University of Hong Kong Press, which has published the works of mainland scholars such as How the Red Sun Rises: The ins and outs of Yan ‘an Rectification Movement by Gao Hua, a professor of history at Nanjing University, and Xu Qingquan, deputy editor-in-chief of Yanhuang Chunqiu, the case of Ding Ling and Chen Qixia’s "anti-Party clique", has gathered a group of excellent mainland scholars’ resources. This university publishing house, which aims at "promoting Chinese and Western cultures and spreading ancient and modern knowledge", is a non-profit academic publishing institution. In the past 30 years, it has published a large number of academic works in both Chinese and English, with authors ranging from Qian Mu and Xu Zhongyue to William Theodore de Bary and Needham. Its topics span from traditional China culture to contemporary China studies, and it has established a stable global sales channel.

　　Gan Qi, president of The Chinese University of Hong Kong Press, told China Newsweek that the press followed the anonymous review system of western university press, and the manuscripts of academic works provided by scholars all over the world must be anonymously reviewed by at least two experts in the industry and submitted to the Academic Books Editorial Committee for final approval before they can be accepted for publication or published after being revised by the author. The editorial department, reviewers and academic committees are integrated to ensure that the manuscript has new ideas or new materials, and in short, it has promoted and contributed on the basis of research in the same field. It is under the guarantee of this system that the publications of this society can maintain the content quality and diversified positions for a long time, which has stimulated the academic thoughts in the mainland.

　　The booths of The Chinese University of Hong Kong Press, Hong Kong Oxford University Press, Hong Kong Commercial Press and Hong Kong Sanlian Bookstore are still the favorite bookstall for mainland readers. ★

　　Cctv news(Reporter Li Wenxue): According to the requirements of the "Class B and B Tube" general plan notice of the comprehensive group of the State Council Joint Prevention and Control Mechanism and the "novel coronavirus Infection Prevention and Control Plan (10th Edition)", on January 9th, the Harbin Leading Group Command issued a notice on optimizing and adjusting the nucleic acid detection strategy, requiring that no nucleic acid should be done unless necessary, at least one 24-hour nucleic acid detection point should be set up in all districts and counties, and personnel of key institutions should carry out antigen or nucleic acid detection.

　　According to the notice, it is required to insist on not doing nucleic acid unless necessary, and no longer carry out nucleic acid screening for all staff. Community residents are "willing to check and check" as needed. The cost of nucleic acid testing for personnel and medical personnel in key institutions such as nursing homes and welfare homes shall be borne by the competent department of industry according to the requirements of "who is in charge, who is responsible and who pays"; Other people will pay for nucleic acid testing from January 10, 2023.

　　All districts and counties (cities) should rely on community health service centers or township hospitals to set up enough convenient nucleic acid detection points, and at least one 24-hour nucleic acid detection point should be set up to facilitate the needs of the public. All nucleic acid detection points should be set in place before January 10. All districts and counties (cities) shall set up at least one testing point that can provide Chinese and English nucleic acid testing reports to meet the needs of citizens for nucleic acid testing abroad.

　　Medical institutions should carry out antigen or nucleic acid detection for outpatients (emergency) with fever and respiratory infection symptoms, hospitalized patients with severe and high risk, and symptomatic medical staff.

　　During the epidemic period, the staff in places where vulnerable people are concentrated, such as pension institutions and social welfare institutions, will carry out full-time nucleic acid testing twice a week, and the people who are cared for will carry out antigen or nucleic acid testing twice a week. The testing of agency staff and people who are cared for will be carried out alternately every other day, or it can be carried out according to the requirements of the competent authorities of the industry. Nucleic acid detection of people in other industries shall be carried out in accordance with the requirements of the competent department of industry.

　　The elderly aged 65 and above, long-term hemodialysis patients, severe diabetes patients and other high-risk community residents, infants under 3 years old and other people need to carry out antigen testing after symptoms such as fever and respiratory infection, or go to convenient nucleic acid testing points set up in the community for nucleic acid testing. Just as residents are infected, other people can carry out antigen testing every day for 3 consecutive days.

　　After other residents have symptoms such as fever and respiratory infection, they can carry out antigen testing on their own as needed, or go to convenient nucleic acid testing points set up in the community for nucleic acid testing.

　　Foreigners enter the gathering place of vulnerable people, check the negative certificate of nucleic acid test within 48 hours and carry out antigen test on the spot; Enter all kinds of business premises, commercial stores, government agencies, enterprises and institutions, and no longer check the negative certificate of nucleic acid detection.

Compared with previous years, this year’s 618 is still a lot of excitement. As the first mega-event promotion node after the lifting of the epidemic control, it is also the 20th anniversary of the founding of JD.COM. At the party on June 18th, the new CEO of JD.COM, Xu Ran, Chairman of Gree Electric, Dong Mingzhu and others all attended.

At the party, Dong Mingzhu also announced that Gree Electric will cooperate with JD.COM in all categories, and strive to bring better products to users. At the party, Dong Mingzhu, as always, advertised his products:"Gree has been striving to provide better products. After all, only Gree’s air conditioners in the world don’t blow people."

Source: Gree

When it comes to air conditioning, the best-selling brands in everyone’s impression are traditional white goods manufacturers such as Gree, Midea and TCL, among which Gree is famous for focusing on the air conditioning market. It is estimated that many people still remember the advertising words "Gree, master the core technology".

There is a saying that Gree air conditioners do sell well. In JD.COM’s air conditioner sales list, Gree is the manufacturer with the most products in the top ten, and only two air conditioners with a price of more than 3,000 yuan are Gree. In Tmall’s hot-selling list, Gree is also on the list.

What did Dong Mingzhu say: "Gree air conditioners don’t blow people"? Does Gree really rely on this to win the recognition of users?

Air conditioning doesn’t blow people, what black technology?

For Xiao Lei, who lives in the south, air conditioning is a life-saving tool in summer. Since April in Guangzhou, the temperature may be higher than 30 degrees, and in the next six months, it is basically normal for the highest temperature to exceed 30 degrees. It can be said that the time of blowing air conditioning is close to half a year.

Friends who often blow air conditioners know that although the air conditioner is good, it is uncomfortable to blow it too much, especially when the air outlet of the air conditioner is facing you. Even in hot summer, as long as the operation of the air conditioner is still normal, you will start looking for the air conditioner in less than 10 minutes to see if you can change the wind direction of the air conditioner and stop blowing it on your head.

The cold air of air conditioner blowing directly on the human body will cause the somatosensory temperature to drop rapidly, and it only takes a short time for you to feel the coldness like winter in summer. Many netizens even bluntly said that direct air-conditioning blowing will give them headaches. Sometimes they forget to adjust the air-conditioning wind direction before going to bed, and get up the next day with a headache and a cold.

Source: VEER

Gree’s propaganda really poked a lot of people’s pain points. After all, if you can make yourself sleep more comfortably at the same price, why not?

Generally speaking, the design of "not blowing people" is called "soft wind" in the industry, and there are many brands promoting the function of soft wind. Xiaomi, TCL and other brands all have products featuring the function of "soft wind". Generally speaking, it is realized by the design of soft wind plate and upper blowing. As long as the air duct is changed, the demand of "air conditioning does not blow people" can be easily realized.

However,What Dong Mingzhu wants to say is obviously more than this. What she said "air conditioning doesn’t blow people" may be more a summary of Gree air conditioning’s technical strength, product design and user demand.Technically speaking, the long-term cold air blowing directly is largely due to the lack of refrigeration capacity of air conditioners, which leads to the inability to cool the room quickly and has to extend the cooling time.

Source: VEER

The "core technology" that Gree has been promoting actually refers to Gree’s air conditioning compressor technology. As the core of air conditioning, the performance of the compressor itself directly determines the cooling and heating effects of air conditioning. In some real-life tests, Gree’s air conditioners are indeed among the best in cooling speed.

Simply put, just let the room reach the set temperature in a short time, then the air conditioner can enter the maintenance mode with low power consumption, and only need to keep the room temperature with low air volume. If the cold wind blows for a short time, it will naturally not give people a strong coolness, which coincides with the requirement of "not blowing people".

More efficient air-conditioning compressor, with the design of flexible air plate and upper air outlet, makes Gree air-conditioning give users a better experience when cooling. Perhaps this is what Dong Mingzhu said, "Only Gree’s air conditioners don’t blow people", and behind it is also the confidence in Gree’s technology and products.

However, whether Gree air conditioners sell well is because they don’t blow people, I’m afraid there is still a question mark.

Which air conditioners are more popular in this 618?

Writing here, Xiao Lei can’t help wondering, what are the most popular air conditioners in 618? What are the functions of the new air conditioner now? Judging from the total sales list of JD.COM, the top three are Gree, Xiaomi and Midea, and their prices are all below 3,000 yuan, all of which are 1.5-horse hanging air conditioners.

Source: JD.COM

Judging from the total sales record of the list, Gree and Xiaomi are cliff-leading, both of which have sold more than 200,000 pieces. It is not an exaggeration to say that these two products are the most popular air conditioners of 618. On the product introduction page,After a brief summary, Xiao Lei found that the selling points of the two are actually very similar: silence, rapid refrigeration, frequency conversion and power saving, and self-cleaning..

The biggest difference between the two is that Xiaomi, who has been deeply involved in the field of smart home appliances, has added a remote Zhilian function to his air conditioner, which can be remotely controlled through apps such as Mijia, which is much more convenient than traditional air conditioners, even if he forgets to turn off the air conditioner when going out, he can also remotely operate it. Gree, on the other hand, doesn’t support it, and it needs the help of an additional infrared remote control gateway.

Generally speaking, the functions of the two air conditioners are very similar. In the past two years, the internal and external machines with special functions were self-cleaning. Now, they have become the standard of two thousand yuan air conditioners, which makes people feel a little overwhelmed by the air conditioning industry. Moreover, in Internet home appliance brands, intelligent interconnection has become a standard product, but traditional home appliance manufacturers often only carry intelligent interconnection systems on high-end product lines.

Looking at other products in the list, the functions are basically the same, and the main selling points are very similar. As for the biggest reason to guide users to make choices, I am afraid it is price and brand power. In terms of price, it can be seen that except Gree, most of the hot-selling air conditioners are between 2,000 and 3,000 yuan, while Xiaomi is the cheapest 1.5 air conditioners on the list with a bottom of 1,879 yuan.

Basically, at present, when users choose air conditioners, they still value power saving, power, durability, etc., and have low requirements for some new functions.Of course, there are also some products with "new functions" in the list. For example, Haier’s Jingyue series is equipped with intelligent light sense sleep protection function, which will automatically adjust the buzzer and indicator brightness of the air conditioner after turning off the lights to ensure that the user’s sleep is not disturbed.

Source: JD.COM

From the actual experience, it may be a function that is better than nothing for most people, but it is of great significance to some sensitive friends with poor sleep quality. In addition, in this year’s air-conditioning market, there are many more products advertised with functions such as "fresh air" and "plasma sterilization", and some high-end users will also consider the extra skills of air-conditioning.

In the high-end air-conditioning market, air-conditioning is no longer a simple appliance for cooling and heating. Some users also hope that it can also serve as a new fan, air purifier and other products to keep indoor air clean. The pursuit of health by users is becoming a new direction in the high-end air-conditioning market.

In addition, intelligent voice control, modular customization and other functions have begun to appear one after another. In the high-end market, these new designs and functions are good ways to attract users.

However, on the whole, most manufacturers are still doing "icing on the cake" before there is a big change in the air-conditioning market today. And in most cases, a 2000-3000 yuan on-hook can meet the cooling/heating needs of the room. As for those extra functions, to be honest, it is not as attractive as reducing the price in 500 yuan.

　　At 17: 00 on December 28th, the Information Office of Xi ‘an Municipal Government held a press conference on the joint prevention and control of epidemic situation in COVID-19 (Game 39), attended by Lv Yongpeng, deputy director of Xi ‘an Health and Wellness Committee, Yang Yongtao, deputy head of Chang ‘an District Government, and Guo Xiaohui, deputy director of High-tech Zone Management Committee, to report the latest situation of epidemic prevention and control in Xi ‘an.

　　The press conference revealed that starting from December 28, Yanta District, Chang ‘an District and High-tech Zone will conduct a regional nucleic acid screening every day.

　　At the press conference, Lv Yongpeng, deputy director of Xi ‘an Health and Health Commission, introduced that at 12 o’clock on December 27th, Xi ‘an started a new round of nucleic acid screening. By 12 o’clock on the 28th, a total of 12,317,000 people had been sampled, and the result was 11,347,800.

　　In this round of nucleic acid screening, a total of 5,077 sampling points and 11,669 sampling stations were set up, with more than 31,000 sampling personnel and 132,900 service support personnel, with a daily detection capacity of 1.6 million tubes. The workflow of each sampling point is standardized, guiding and persuading the masses to keep "one meter line" and scanning code, so that the sampling work runs efficiently.

　　With the effective organization of staff and the active cooperation of citizens and friends, the efficiency of nucleic acid sampling has been greatly improved. From 12: 00 to 20: 00 on the 27th, a total of 11,080,800 people were sampled, and more than 11 million people were sampled in 8 hours. Yanta District, Chang ‘an District and High-tech Zone will conduct nucleic acid screening once a day from December 28th. According to the situation, Lianhu District will increase the frequency of nucleic acid screening in the whole region; 1250 sampling personnel were transferred from other districts, counties and development zones to support nucleic acid screening in the above four districts, counties and development zones.