Mercedes-Benz AMG Project ONE is so powerful, how did it happen?

  

This year, Project ONE, the 50th anniversary model of AMG, received high attention. There are two main reasons: first, it is expensive, and only 275 sets are limited to production, and the price is 2.27 million euros.

Secondly, the data is too strong. This car is equipped with F1 racing car that should only appear on the track. It will be more than 1014 horsepower, and the acceleration of 100 kilometers will take 2 seconds, while the acceleration of 0 to 200 kilometers will only take 6 seconds. What’s even more incredible is that this car is only 1.6 liters, with four motors.

  

So the question is, how does this sports car make the power so strong?

First of all, the power system of AMG Project ONE is a hybrid system consisting of a 1.6T V6 and four motors. This one originated from the F1 Championship for the 2015 season. Lewis hamilton also won the championship this year with this excellent performance.

According to the published data, 1.6T booster plus 4 motors, the total reached 746kW. One of the four motors provides pumping power for the turbine, which is 90kW. This motor does not participate in direct work to drive the whole vehicle, but provides power source for the electronic turbine. The other three motors are 120kW, which can directly provide power for the whole vehicle. This hybrid mode is a parallel mode.

  

The advantage of parallel mode is that the energy loss is small, and each motor can drive the whole vehicle independently. In addition to transmission loss and system error, the sum can be calculated by superposition. This power system is about 746kW, minus the superposition of three motors of 360kW, so this 1.6 liter will reach 386kW.

Is it ridiculous? This is something that you can’t even think about. Generally, it takes more than 4L to achieve 386kW, but it can be achieved on a 1.6L platform, just like a 3-year-old child lifting a weight of 80kg.

The maximum NA of conventional 1.6L is only about 90kW, and the rotating speed is 6000rpm. If the rotating speed is doubled to 12000rpm, the times of doing work per unit time will be doubled. Plus, if it is increased by 40%, it will reach 252kW.

  

So how did this model achieve 386Kw? This AMG with a F1 heart not only uses exhaust gas to drive the turbine to increase the intake density, but also uses a 90kW motor to drive the electric turbine to increase the intake density, so it is entirely possible to reach 386kW.

This is the secret weapon of Super Engine with super power, but there are many problems to be solved to make it work normally. The first is inertia force. With the increase of rotational speed, the average speed is 7-12M/S, and the acceleration can reach about 200 g, while the rotational speed of Super Engine is twice or more than that of the conventional 1.6L. If designed according to the routine, the acceleration can reach 400 g, which is a great design challenge.

How does Super Engine do to overcome such a large inertial force? First of all, this is the advantage of a V6, V-type. For the whole vehicle, it can lower the center of gravity, and the effect is better. For me, first of all, the V-shape can decompose the inertial force into two opposite directions in the horizontal plane, and the inertial force can cancel each other out. So we only need to overcome the vertical component.

  

Secondly, 1.6L is divided into six cylinders, and the volume of each cylinder is reduced from 0.4L to 0.266L. The mass and volume of the connecting rod can be made smaller, so the rotation speed can be improved and the inertia force can be reduced.

In addition, the moment arm of is 1/2, so the Super Engine must be as short as possible, and F1 will generally set/to 2.5, so that the inertia force will be reduced at high speed.

In addition, the system, the opening and closing of the conventional camshaft drive, can no longer meet the reliability requirements at such a high speed, plus the force attenuation, the conventional steel is completely incompetent for this work. Therefore, a high-pressure nitrogen pressure tank must be equipped separately, and the pressure release gas pushing mechanism of the pressure tank can be controlled by calculating the opening and closing time of the electromagnetic valve, so that the reciprocating motion can be carried out quickly.

Super Engine rotates at 12,000 revolutions per minute, ignites 200 times per second, and opens and closes 200 times per second. The strength and reliability requirements of these core components, as well as the accuracy of ignition design, are very high, among which titanium alloy is the best choice for material selection.

  

It needs to be emphasized here that the increase of intake density is directly proportional to the temperature in the intercooling system of this car. The intake air volume of 4.5L is inhaled in a unit time of 1.6L According to the conventional conversion, the intake pressure will reach about 3 bar, and the temperature after vortex will be much higher than that of traditional supercharging, so it is necessary to make a special design for the intercooling system to cool the intake temperature.

Generally, the service life of F1 racing car is 1000 kilometers, over after the runway is completed, which is caused by different design concepts. F1 is to pursue the ultimate speed and win the race. If the speed is designed to be above 15,000 rpm and other performance is sacrificed to improve the speed, such as reducing the weight of all parts, its reliability will not be considered, because winning the game is more important than everything else.

The service life of AMG Project ONE is 50,000 kilometers, which is much longer than that of F1′ s1,000 kilometers. I think there are two main reasons: first, the speed is reduced to about 11,000 rpm, so the use environment of parts is much milder than that of F1; Second, the use environment of the car, F1 is basically the biggest running on the track, and the maximum potential of F1 is fully exerted. However, AMG Project ONE cannot run at full speed within its life cycle, but should have its own durable working conditions.

  

Finally, the technology of F1 events will be decentralized to the civilian field, bringing us such a high-performance product. In my opinion, this is just a high-end souvenir for the 50th anniversary of AMG, to let the world know the technology and look forward to it. However, it didn’t achieve real civilian use, 50,000 kilometers, and the conventional car was only maintained for 3 ~ 5 times, but AMG Project ONE had to change the powertrain to continue to use. In addition, the pure electric mode only lasted for 20 kilometers, which was a bit embarrassing.

Therefore, AMG Project ONE can improve the reliability and battery technology to be truly commercialized.

finish

It is unusual for the official who was "double-opened" to report that the promotion of Cordyceps failed to control the religious Buddhism

       CCTV News:On September 16, 2019, the website of the State Supervision Commission of the Central Commission for Discipline Inspection released a message: Hu Hongchun, former member of the Standing Committee of Wuhan Municipal Committee, former secretary of the Working Committee of Wuhan Development Zone and former secretary of Hannan District Committee, was expelled from the Party and public office.

       After investigation, Hu Hongchun deviated from the party’s purpose, lost his ideals and beliefs, was disloyal and dishonest to the party, violated political discipline, transferred, concealed and destroyed stolen money, and resisted organizational review; Violation of organizational discipline, failing to truthfully explain the problem when organizing letters and inquiries; Violating the discipline of honesty, engaging in paid intermediary activities such as selling Cordyceps in violation of regulations, and accepting gifts that may affect the fair execution of official duties; Violation of work discipline, ineffective implementation of laws and regulations on the management of religious affairs, and important leadership responsibility for the illegal construction of places for religious activities and the neglect of religious Buddhism within the jurisdiction, resulting in adverse effects and major economic losses; Violate life discipline. Violation of national laws, taking advantage of his position to seek benefits for others, asking for and illegally accepting other people’s property, the amount is particularly huge, and he is suspected of accepting bribes; Abuse of power, illegal provision of assistance to criminals for parole, resulting in criminals committing a variety of illegal and criminal acts after being paroled, seriously damaging the national legal authority and judicial credibility, causing adverse social impact, suspected of abuse of power.

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       In this bulletin, several items are rare and attracted everyone’s attention at the first time.

       First of all, the item "engaging in paid intermediary activities such as selling Cordyceps in violation of regulations" is very eye-catching. According to Hu Hongchun’s public resume, in September 2004, he served as deputy secretary of Huangpi District Committee (from June 2004 to June 2007, he served as secretary of Naidong County Committee of Xizang Autonomous Region). As we all know, Xizang Autonomous Region is one of the main producing areas of Cordyceps sinensis in China.

       Secondly, it can be said that it is very rare for this content to appear in the notification of officials who have fallen off the horse. According to the public resume, Hu Hongchun served as member of the Standing Committee of Wuhan Municipal Committee and Minister of United Front Work Department in December 2017; In December 2018, he served as member of the Standing Committee of Wuhan Municipal Committee, Minister of United Front Work Department, Secretary of Working Committee of Wuhan Development Zone and Secretary of Hannan District Committee; Since February 2019, he will no longer serve as the head of the United Front Work Department of Wuhan Municipal Committee.

       According to the website of the United Front Work Department of Wuhan Municipal Committee of the Communist Party of China, the United Front Work Department of Wuhan Municipal Committee of the Communist Party of China was established in August 1950 and is the functional department in charge of the United front work of Wuhan Municipal Committee of the Communist Party of China. The main functions and tasks are to implement the line, principles and policies of the Central Committee, the Provincial Party Committee and the Municipal Party Committee on the United front, strengthen ties with democratic parties, federations of industry and commerce, personages without party affiliation and relevant people’s organizations in the city, actively carry out United front work in various fields such as non-public economy, democratic parties, ethnic religions, Hong Kong, Macao and Taiwan, overseas, non-party intellectuals and new social strata, win people’s hearts, gather strength, mobilize all positive factors, and turn negative factors into positive ones, which is formulated by the Municipal Party Committee for the realization.

       In addition, the bulletin also mentioned a very hateful behavior of Hu Hongchun — — Abuse of power, illegal provision of help for criminal parole. We have noticed that on March 18th, 2019, Li Shengqiao, former Party Secretary and Chairman of huangpi district CPPCC, was expelled from the Party and public office. At that time, it was reported that he "took advantage of his position as secretary of the Political and Legal Committee of huangpi district, engaged in malpractices for personal gain, abused his power, provided help to criminals who violated the rules of parole, seriously damaged legal authority and judicial credibility, and caused adverse social impact, and was suspected of abusing his power". As a leading cadre in party member, Li Shengqiao lost his ideals and beliefs, deviated from the party’s purpose, abused public power, and acted as a "protective umbrella" for people involved in black and evil; The expansion of selfish desires, accepting bribes, seriously violating the party’s discipline and national laws, and being suspected of duty crimes, and failing to converge and stop after the 18 th National Congress of the Communist Party of China, the nature is bad and the circumstances are serious, which should be dealt with seriously.

       According to public information, from October 2001 to October 2011, Li Shengqiao served as member of the Standing Committee of huangpi district District Committee and secretary of the Political and Legal Committee of the District Committee. From October 2011 to November 2011, he served as Party Secretary of huangpi district CPPCC and Secretary of the Political and Legal Committee of the District Committee; From November 2011 to November 2016, he served as Party Secretary and Chairman of huangpi district CPPCC; Since November 2016, I have retired to the second line.

       In October 2001, Hu Hongchun served as member of the Standing Committee of Wuhan Huangpi District Committee and director of the office; In September 2004, he served as deputy secretary of Huangpi District Committee of Wuhan City; In November 2007, he served as deputy secretary of the Working Committee of the Wuhan Municipal Committee (bureau level); In August 2009, he served as deputy secretary and acting district head of Huangpi District Committee of Wuhan City; In December 2009, he served as deputy secretary and district head of Huangpi District Committee of Wuhan City; In September 2011, he served as secretary of Huangpi District Committee of Wuhan.

       On September 28, 2018, Li Shengqiao was suspected of serious violation of the law and accepted the disciplinary review and supervision investigation by the Supervision Committee of the Hubei Provincial Commission for Discipline Inspection.

       On March 21, 2019, Hu Hongchun was suspected of serious violation of discipline and duty, and was subject to disciplinary review and supervision investigation.

       The two men’s working experiences overlap, and both of them mentioned the same crime in the "double-opening" briefing, which has to be thought-provoking.

How to allocate long-distance tickets and short-distance tickets? The official answer is coming!

CCTV News:According to the official news of China Railway,Official answerHow to allocate long-distance tickets and short-distance tickets.

  Summer vacation is just in time.

  Many people say that train ticket sales are too hot.

  Short-distance tickets are often not available.

  Mingming 12306 shows that there are tickets for the whole journey.

  But the stopover can only be "standby"

  What the hell is going on here?

  How much are long-distance tickets and short-distance tickets?

  Due to the "cluster" of passenger travel demand during the summer vacation, the transportation capacity is tense in stages. In this case, the railway department will give priority to the long-distance passengers from the starting station to the terminal to maximize the utilization of transportation resources.

  If the short-distance ticket is sold openly, it will directly occupy the ticket amount of long-distance passengers, and there will be fewer opportunities for long-distance passengers with rigid demand and small choice. At the same time, long-distance tickets will be sold randomly in sections, which will inevitably cause some sections to be idle and the transportation capacity will not be fully utilized.

  Of course, the railway department will also take into account the needs of short-distance passengers. When the long-distance ticket amount is sufficient, it will dynamically adjust the ticket amount according to the change of demand, and automatically transfer some tickets to stations along the way in different periods to meet the needs of short-distance passengers.

  How to allocate tickets for each intermediate station along the route?

  The basic principle of railway ticket allocation is to make it as convenient as possible for passengers along the route to purchase tickets and make the best use of railway transport resources, which is mainly based on the historical passenger flow and ticket pre-sale at the departure station and stations along the way.

  According to this, the railway department will dynamically optimize and adjust the ticketing strategy. When the pre-sale of long-distance tickets fails to meet expectations, the railway department will adjust some tickets to stations with demand along the way; When the demand for pre-sale of departure station tickets is relatively strong, the reservation of departure station tickets will be increased.

  Since the summer vacation this year, the national railways have operated 10,169 passenger trains every day, an increase of 14.2% compared with the same period in 2019, and the overall efficiency of the road network has been further improved, providing protection for summer passenger transportation.

  What if I can’t buy a through ticket?

  In order to meet the travel needs of passengers who have no through train, or who have a through train but have no spare tickets, Railway 12306App provides a transfer service function. After the passenger submits the travel demand, the system will show the differentiated railway transfer routes to the passenger according to the train schedule, the remaining tickets, and the time consumption of public transportation between different railway stations in the same city.

  Transfer in 15 minutes. Is that enough time? Sure! At present, the railway department has increased the number of convenient transfer stations that can realize transfer without leaving the station to 100, and opened convenient transfer passages in the stations, thus avoiding the trouble of passengers leaving the station first and then entering the station through security check.

  Alternate ticket purchase helps you.

  At present, passengers can submit two alternate tickets for adjacent dates to the same station or different stations in the same city every day, from the previous two to five.

  Never "buy short and multiply long"!

  In order to ensure the safety of train operation, railway vehicles have certain passenger capacity restrictions. For safe, high-speed and smooth running high-speed trains, the restrictions on passenger capacity are more stringent.

  At the peak of passenger flow, if a large number of passengers who buy short-distance tickets do not get off at the station, the number of carriages will be overcrowded, which will seriously endanger the safety of train operation and affect the normal transportation order.

Henan police rumored that "college students marry classmates and mothers"

  Xinhua News Agency, Zhengzhou, January 4th, New Media Specialist (Reporter Ma Yizhen) In response to the recent online incident of "Henan college students marrying classmates’ mothers", Weibo, the official of Henan Provincial Public Security Bureau, released a message saying that similar rumors have been spread in many places for several years and are false news.

  Recently, a news that "Henan college students marry classmates’ mothers" attracted attention on the Internet. According to the news, a handsome 21-year-old college student married a 55-year-old divorced middle-aged aunt in a hotel in Henan. Incredibly, this middle-aged aunt is actually the biological mother of the groom’s college classmates.

  The news also said, "It turns out that the truth behind the incident is actually like this. The groom is young and handsome, while the bride looks very young at the age of 55, just like a young girl in her twenties … …”

  After testing, it is found that there have been similar articles since 2013, involving different places such as Guangzhou, Wuxi and Pingtan, and the pictures are the same, the story is the same, and most of the words are the same. These articles all mention that classmates and mothers use some kind of skin care products, carry out beauty treatment and so on.

  Some experts in journalism and communication believe that, in view of the proliferation of fake news, a governance and restraint mechanism should be established, and strict control and strict investigation should be carried out through legal and administrative penalties.

Global News: US stocks opened higher and closed lower. NVIDIA’s revenue "Thunderstorm" fell more than 6%

  US stocks opened higher and went lower on Monday. The S&P 500 Index and Nasdaq closed down by nearly 1% in intraday trading, while the Dow rose slightly by 0.09%. Brent crude oil rose by nearly 2%; New york gold futures re-entered the $1,800 mark. The strong employment data released last week made investors hold their breath for the US CPI (released on Wednesday), while the NVIDIA revenue warning dragged down the performance of the index.

  NVIDIA, a graphics card giant, gave a pre-market performance warning on Monday, and predicted that its revenue in the second quarter would be US$ 6.7 billion, down 19% month-on-month and up only 3% year-on-year, mainly due to the sluggish performance of the game business (games+mining graphics cards) (revenue decreased by 44% month-on-month and decreased by 33% year-on-year). Overall revenue was much lower than NVIDIA’s previous forecast of $8.1 billion, and the stock closed down 6.3% (it fell over 9% in intraday trading), which also dragged down the Nasdaq. The company will hold a financial report meeting on August 24th.

  [overnight U.S. stocks]

  Among large-scale technology stocks, Apple fell 0.29%, Microsoft fell 0.92%, Amazon fell 0.99%, Google A fell 0.14% and Meta rose 1.88%.

  Among the large Chinese stocks, Alibaba fell by 1.86%, Baidu by 1.03%, Netease by 0.54%, Pinduoduo by 5.13%, Weibo by 1.42%, iQiyi by 0.26%, Good Future by 4.09% and New Oriental by 8.57%.

  [global index]

  [global goods]

  The main contract of crude oil in the previous period closed at 669.20 yuan per barrel overnight, up 1.72%.

  Overnight, the Shanghai gold main contract closed up 0.73% to 391.00 yuan per gram; The main contract of Shanghai Bank closed up 3.51% to 4,518.00 yuan per kilogram.

  [overnight news]

  American consumers’ inflation expectations dropped significantly in July, and the inflation expectations will drop to 6.2% in the coming year.

  The sharp drop in gasoline prices and the growing belief among Americans that the rapid rise in food and housing prices will also subside in the future, American consumers’ expectations of future inflation dropped significantly in July.

  According to the monthly consumer expectation survey of the Federal Reserve Bank of new york, the inflation expectation of the respondents in the coming year is 6.2%, which is the largest monthly decline in the survey history; 3.2% in the next three years. Although these figures are still high compared with the historical range, they are significantly lower than the results of 6.8% and 3.6% in the June survey.

  In August, the investor confidence index in the euro zone recorded another negative value, and the economic downturn expectation intensified.

  According to the latest report of German market research institute Sentix, the investor confidence index in the euro zone recorded -25.2 in August, slightly rising from the previous value of -26.4, but still lower than market expectations.

  According to the report, "the euro zone economy is still in a difficult situation. A slight rebound does not mean that the alarm is lifted, and the possibility of recession is still high."

  EU submits "final text" on resuming the implementation of the Iranian nuclear deal.

  On Monday, the EU submitted a "final text" on resuming the implementation of the 2015 the Iranian nuclear deal to the participants in the negotiations on resuming the implementation of the comprehensive agreement on the Iranian nuclear issue, and expected all parties to make a political decision on this "final text".

  Borrell, the EU’s High Representative for Foreign Affairs and Security Policy, posted on social media that all the contents that can be negotiated have been negotiated and are now written into the "final text". All parties need to make political decisions on every technical issue and every detail in the "final text". If there is no objection, you can sign the agreement.

  The United States seized a Russian oligarch’s private jet worth $90 million

  According to CCTV news, foreign media reported that the U.S. federal prosecutor had taken action to seize Russian oligarch Andrei Skoch’s Airbus A319 worth $90 million.

  According to reports, Andrei Sarkozy is known as "the richest man in Duma" and has been a member of the Russian National Assembly since 1999. The United States has imposed sanctions on him since 2018, claiming that Sarkozy has "long-term ties with Russian organized criminal groups". After the conflict between Russia and Ukraine broke out, the United States imposed further sanctions on Sarkozy and its assets.

  USAID: Ukraine will receive an additional $4.5 billion in funding.

  On August 8, local time, the United States Agency for International Development (USAID) issued a statement saying that it would provide an additional $4.5 billion to the Ukrainian government, bringing the total amount of US aid to Ukraine since the outbreak of the Russian-Ukrainian conflict in February to $8.5 billion.

  According to the statement, the funds will flow to the Ukrainian government in batches through the coordination of the World Bank and the US Treasury Department, and the first batch of funds of 3 billion US dollars will be paid from August.

  The strong employment report raised the Fed’s expectation of raising interest rates by 75 basis points, and then became the basic situation. Citigroup even thought that raising interest rates by 100 basis points.

  Faced with the strong employment report released last Friday, economists from JPMorgan Chase, Evercore ISI and LH Meyer think that the Fed may raise interest rates more sharply this year, and Citigroup even expects the Fed to raise interest rates by a full percentage point in September.

  Michael Feroli of JPMorgan Chase and Derek Tang of LH Meyer now predict that the Fed may raise interest rates by 75 basis points at its meeting on September 20-21, compared with the previous forecast of 50 basis points. Evercore analysts led by Krishna Guha expect to increase by 25 basis points this year and raise the upper limit of the target range of the federal funds rate to 3.75% by December.

  [company news]

  NVIDIA’s revenue in the second quarter is expected to be 6.7 billion US dollars, resulting in a 19% decline from the previous month.

  NVIDIA said that due to the sluggish game business, revenue in the second quarter will drop by 19% from the previous quarter, only increasing by 3% year-on-year, reaching $6.7 billion, far below the company’s previous guidance of $8.1 billion, which caused the company’s share price to fall by more than 6% (once fell by more than 9% in intraday trading).

  NVIDIA predicted that the game business revenue in the second quarter will reach 2.04 billion US dollars, down 44% from the previous month and down 33% from the same period last year. In contrast, data center business revenue will reach 3.81 billion US dollars, up 1% from the previous month and up 61% from the same period last year.

  Federal Aviation Administration: Delivery of Boeing 787 Dreamliner will be restarted in "the next few days"

  The Federal Aviation Administration (FAA) said on Monday that Boeing is expected to resume the delivery of its 787 Dreamliner in the next few days.

  Since the end of 2020, the Boeing 787 Dreamliner has been found to have many quality problems, and the delivery has almost stopped.

  The FAA said in a statement: "Boeing has made necessary changes to ensure that the 787 Dreamliner meets all certification standards. The FAA will inspect each aircraft before issuing airworthiness certificates and approving delivery. "

  Ruixing’s revenue in the second quarter increased by 72% year-on-year, and its profit margin greatly improved, with nearly 7,200 stores.

  Luckin Coffee’s total net income in the second quarter was 3,298.7 billion yuan, a year-on-year increase of 72.4%. There were 615 new stores in this quarter, and the total number of stores reached 7195.

  According to the financial report, as of the second quarter, there were 4,968 self-operated stores and 2,227 affiliated stores in Luckin Coffee. Luckin Coffee’s business growth capacity continued to improve, with the same-store sales growth rate of self-operated stores reaching 41.2%. In addition, the profitability of Luckin Coffee has been further improved, with the profit rate of self-operated stores reaching 30.6%, which is significantly higher than that of 23.1% in the same period in 2021.

  The average number of trading customers in this quarter increased by 68.6% year-on-year to 20.7 million. According to American Accounting Standards (CAAP), the operating profit of Luckin Coffee in the second quarter was 241.6 million yuan, and the operating profit rate under American Accounting Standards (GAAP) was 7.3%, while the loss in the same period in 2021 was 47.5 million yuan.

  Alibaba: Voluntary conversion to dual major listing on the Hong Kong Stock Exchange is expected to be completed before the end of the year.

  Alibaba announced on the Hong Kong Stock Exchange that it would voluntarily switch to dual major listing on the Hong Kong Stock Exchange, and this application has been confirmed by the Hong Kong Stock Exchange. The effective date of the major conversion is expected to be before the end of 2022.

  Ali said that after the relevant procedures are completed, Alibaba will become a dual-listed company with american depository receipts on the new york Stock Exchange and ordinary shares on the Hong Kong Stock Exchange.

  At that time, American-listed depositary shares and Hong Kong-listed common shares can be exchanged, and investors can continue to choose to hold Alibaba shares in one form or another.

Class 2A carcinogen was detected in the drug! The problem valsartan API has been recalled.

  Cctv news: Pay attention to the situation of valsartan in Zhejiang Huahai Pharmaceutical Company. Yesterday (July 29th), the spokesperson of National Medical Products Administration introduced the situation of trace N- nitrosodimethylamine (NDMA) impurities detected in valsartan raw materials of Zhejiang Huahai Pharmaceutical Co., Ltd. 

  On July 6th, Zhejiang Huahai Pharmaceutical reported to National Medical Products Administration that a small amount of N- nitrosodimethylamine (NDMA) impurities were detected in the raw materials of valsartan for export, and voluntarily disclosed relevant information to the public according to relevant regulations and requirements.

  Zhejiang Huahai Pharmaceutical Co., Ltd. immediately suspended the release and delivery of all valsartan raw materials in the domestic and international markets after detecting the impurity, and initiated the measures of voluntary recall. As of July 23, Zhejiang Huahai Pharmaceutical has completed the recall of all raw materials in China.

  In 2012 and 2013, the current process of raw materials of this enterprise was approved by the European Drug Administration (EMA) and the US Food and Drug Administration (FDA) respectively.

  Since July 6th, National Medical Products Administration has maintained close communication and contact with the European Drug Administration and the US Food and Drug Administration, paid close attention to the announcements and trends of risk assessment issued by international regulatory agencies, and organized experts to carry out risk assessment.

  According to the toxicological data, the maximum daily intake limit of N- nitrosodimethylamine is 0.1μ G, which is equivalent to the provisional reference limit value of 0.3ppm by the European Drug Administration (calculated by taking 320mg valsartan daily).

  According to the above-mentioned limit value, National Medical Products Administration conducted risk investigation on all the seven domestic manufacturers of valsartan raw materials (including Zhejiang Huahai Pharmaceutical). Except for the impurity of N- nitrosodimethylamine in valsartan raw materials of Zhejiang Huahai Pharmaceutical, the impurity detection value of N- nitrosodimethylamine in other domestic manufacturers of valsartan raw materials was lower than the limit value or was not detected.

  There are 6 pharmaceutical manufacturers involved in the use of valsartan in Zhejiang Huahai Pharmaceutical:

  The valsartan capsule (National Medicine Zhunzi H20103521) produced by Hunan Qianjin Xiangjiang Pharmaceutical Co., Ltd. has not yet left the factory.

  The impurities of N- nitrosodimethylamine in the listed products of the other five manufacturers exceeded the limit, namely

  Valsartan Hydrochlorothiazide Capsule of Chongqing Kangkeer Pharmaceutical Co., Ltd. (National Medicine Zhunzi H20080097)

  Valsartan dispersible tablets of Hainan Huanglong Pharmaceutical Co., Ltd. (National Medicine Zhunzi H20050508)

  Valsartan dispersible tablets of Harbin Sanlian Pharmaceutical Co., Ltd. (National Medicine Zhunzi H20061058)

  Valsartan Hydrochlorothiazide Dispersible Tablets of Jiangsu Wangao Pharmaceutical Co., Ltd. (National Medicine Zhunzi H20090262)

  Valsartan dispersible tablets of Shandong Yijian Pharmaceutical Co., Ltd. (National Medicine Zhunzi H20090319)

  The above five preparation manufacturers have stopped using the raw materials of Valsartan of Huahai Pharmaceutical and recalled relevant drugs according to regulations.

  National Medical Products Administration has asked all provincial food and drug supervision and management departments to urge relevant preparation manufacturers to take recall measures, and disclose relevant recall information on the websites of five manufacturers, including the contact numbers of the enterprises responsible for the recall.

  In order to facilitate the public to know in time whether the Valsartan drugs being used are within the scope of recall, five manufacturers have cooperated with information technology companies and launched the code scanning inquiry function at 22: 00 on July 26, 2018. The product traceability code can be scanned through the mobile APP to realize instant inquiry.

  National Medical Products Administration spokesman stressed that besides the above five preparation manufacturers, other valsartan preparation products are not included in the recall.

  At present, European Union and other multinational drug regulatory agencies believe that N- nitrosodimethylamine belongs to Class 2A carcinogen (that is, there is sufficient evidence in animal experiments, but the evidence is limited), and it may be exposed to this substance in daily life (such as preserved food). Analysis of the drugs involved this time will not cause serious health risks to patients, but for safety reasons, risk control measures such as stopping sales and recalling should be taken.

  On July 27th, FDA issued a notice that patients taking recalled valsartan should continue to take the current drugs until doctors or pharmacists provide alternative drugs or different treatment schemes.

  A spokesman for National Medical Products Administration reminded that patients who are taking valsartan drugs must not stop taking them without authorization, because the risk of stopping taking them without authorization is more direct and serious for patients with hypertension. Whether to stop taking medicine or change medicine must be carried out under the guidance of a doctor. You can contact a doctor to replace other drugs containing valsartan that are not involved in the recall or choose other drugs for alternative treatment.

  National Medical Products Administration requires the relevant provincial food and drug supervision and management departments to continue to follow the relevant provisions of the Measures for the Administration of Drug Recall, urge enterprises to do a good job in product recall and protect people’s drug safety.

Calm response to the employment of college students under the influence of epidemic situation

  Bright picture

  [educational perspective]

  The epidemic has caused many inconveniences in finding jobs.

  For most college students who will graduate in 2020, COVID-19, an unfamiliar word, will be engraved in their memories along with their tortuous job hunting experience. Because of the development of the epidemic in COVID-19, in order to protect students’ health and life safety and prevent the spread of the epidemic, the national education administrative departments and universities have taken emergency measures to limit the flow of personnel, and all kinds of campus recruitment activities have been suspended.

  According to the practice of previous years, the coming March and April was originally the peak period for fresh college students to apply for jobs and sign contracts, but because of the epidemic, the employment and recruitment activities of college students were silent this spring.

  The superposition of all these unfavorable factors undoubtedly affects the job selection of college graduates and the selection of talents by employers, which invisibly increases the pressure of college students’ employment.

  For China’s economic development, the impact of the COVID-19 epidemic on the economy is bound to have a chain reaction, which will be transmitted and reflected in the employment sector — — Not only the temporary communication difficulties between graduates and enterprises and the inability to carry out recruitment activities, but also the demand for employers may be reduced. Of course, some industry sectors, such as medical and health care, environmental engineering, chemical technology and other employment needs are likely to increase.

  The interview and employment pressure of job-seeking students has increased sharply. The silence in March and April, the peak of job hunting, dealt a heavy blow to college students’ employment signing. Because some students and employers have drawn up their initial intentions and need to go to the employer for an interview, but now the unit can’t operate normally, students can’t go out, and the recruitment and interview plans of some companies have also changed, and students are in a dilemma.

  Stuck by the time limit, students who are pursuing further studies are in a dilemma. The postponement of the re-examination of the postgraduate entrance examination has a great influence on students. The uncertainty of whether they can pass the initial examination and whether they can be admitted after the re-examination makes most postgraduate students anxious, fearing that they may miss favorable employment opportunities after falling out of the list.

  At the same time, taking into account epidemic prevention and employment, colleges and universities are facing multiple tests. Up to now, due to the pressure of economic adjustment, the employment rate of graduates who originally signed up to implement employment units is not optimistic. The arrival of the epidemic has made colleges and universities more pressure on epidemic prevention and teaching adjustment under the new situation than before, and the pressure on subsequent employment guidance has undoubtedly increased accordingly. The impact and impact of these pressures on local colleges and universities with the majority of local students will be less than those with scattered students’ origin and employment destination.

  To cope with the pressure of employment, take many measures to promote Qi Li.

  Employment must be promoted by the government, universities, employment enterprises and units, giving full play to their respective advantages in resources, channels and experience. As for the universities directly facing the above employment pressure, how to deal with this year’s new situation?

  Colleges and universities should not panic when they serve college students’ employment under pressure.At present, we can see that under the decisive and correct decision-making and leadership of the CPC Central Committee, the understanding of COVID-19 has gradually deepened, and the fight against the epidemic has achieved initial results. The confirmed cases and suspected cases in high-incidence areas have been running at a low level, and the epidemic situation in most areas has been effectively controlled. I believe that with the support and encouragement of various supporting policies of the state, all economic construction activities will be carried out in an orderly manner. This is the biggest good news for economic activities directly related to employment.

  College students start job hunting and employment rationally and calmly.Then, after the epidemic is controlled, the employment activities of college students that have been temporarily suspended will be restarted, and the suppressed demand for employment will be released again. Therefore, for colleges and graduates, they should gradually become rational, sober and brave from the initial panic, anxiety and sorrow, and there is no need to panic at all. They should have full confidence and calmly and objectively carry out the employment work during the epidemic period according to the arrangement of the national education administrative department.

  Enterprises should promptly strengthen the organization of online employment recruitment activities.Before the epidemic has been completely controlled, in order to prevent large-scale gathering of people, the on-site recruitment activities of various college graduates have been suspended. In this case, colleges and universities should vigorously promote the development of online employment activities, and guide more enterprises to organize more online recruitment activities in a planned way to provide graduates with job opportunities; Students can get job information and enjoy online employment services by browsing national and provincial employment platforms, university employment networks and social recruitment websites.

  Multi-party cooperation to explore innovative employment channels.Colleges and universities should take the initiative to coordinate relevant parties and further organize and implement grassroots projects such as the special post teacher plan, the university student village official, the three supports and one support, and the university student volunteer service plan for the western region; Encourage college students to join the army and serve national defense; Further implement preferential policies such as tuition subsidy for grassroots employment and encourage graduates to work and start businesses at the grassroots level; Establish a docking platform for school-enterprise cooperation and strengthen the docking of talent supply and demand in key areas, major projects, major projects and important fields; Further explore the employment opportunities created by the deep integration of the Internet, big data, artificial intelligence and the real economy, and support graduates to achieve multi-channel employment; Call on employers to hold campus job fairs, take recruitment tests exams, receive graduates’ resumes and practice training through the Internet and other more flexible ways.

  Focus on strengthening the focus on helping students from difficult families.Colleges and universities must actively design and provide one-on-one assistance to poor family graduates, physically disabled graduates and other groups, and carry out targeted job promotion. It is urgent to form a team of relevant university leaders, fully grasp the latest trends of students, regional economy and professional fields, open a hotline for employment consultation and help, and develop a number of online employment guidance courses to do a good job in promoting graduates’ employment, enterprise docking and psychological counseling.

  The epidemic will eventually pass. As long as all parties face it confidently, calmly, optimistically and scientifically, with the overall victory in the fight against the epidemic, the employment situation of college graduates in 2020 will certainly improve and usher in "spring"!

   (Author: Zong Cheng, a postdoctoral fellow at China Academy of Educational Sciences)

The curtain call of "medicine king"! Trillion drug-free track opens a new competition

The year 2023 is of great significance to the drugs for autoimmune diseases and even to the global innovative drug market. With the expiration of patents in key markets, Hummel (adalimumab) will officially hand over the title of global sales champion for 11 years, and the first generation of "drug king" will officially end.

Due to the complex pathogenesis, the number of patients with autoimmune diseases is large and it is difficult to cure. The long-term or even lifelong demand for drugs has spawned a huge market for autoimmune drugs, which has become a hotbed for the growth of heavy drugs.

Under the demonstration effect of "drug king", major pharmaceutical companies around the world have been scrambling for layout in recent years. At present, breakthroughs have been made in the development of new drugs for potential targets such as JAK and interleukin, and the free drug track is expected to usher in a new round of competition. Local innovative drug companies try to gain a place in the domestic free drug market through differentiated distribution of indications and continuous optimization of safety.

The market for self-exempted drugs continues to grow steadily.

Autoimmune system diseases refer to diseases caused by immune response to autoantigens and self-tissue damage. Genetic defects and environmental factors are all important links in inducing autoimmune diseases. The complex disease mechanism leads to a wide variety of autoimmune diseases and a large patient base. At present, there are more than 100 known main disease types, including psoriasis, atopic dermatitis, compulsory spondylitis, rheumatoid arthritis and systemic lupus erythematosus.

As a chronic disease, autoimmune diseases usually do not directly kill people, but it is also difficult to cure them. Such as compulsory spondylitis, systemic lupus erythematosus, etc., once suffering from it, it will be difficult to reverse, which is called "undead cancer". Patients need long-term or even lifelong medication, thus giving birth to the long-term and stable growth of market demand for self-immune drugs.

Based on the financial report data of major pharmaceutical companies, in 2022, there were 22 self-disease-free drugs in the list of TOP100 drugs with global sales scale, of which 10 drugs exceeded $3 billion and the total sales exceeded $70 billion.

According to the statistics of AARDA, patients with autoimmune diseases account for 7.6%-9.4% of the global population in recent years. Jost Sullivan’s statistics show that there are nearly 500 million patients with various kinds of self-immune diseases in the world, and the global self-immune drug market will reach about 132.3 billion US dollars in 2022, which has become the second largest disease market after cancer.

Jost Sullivan predicted that by 2030, the global self-exempted drug market is expected to reach US$ 176 billion, with a compound annual growth rate of 3.6% from 2022 to 2030. Among them, the self-exempted drug market in China is expected to reach nearly US$ 25 billion in 2030, a tenfold increase compared with 2020, which is an important incremental source of global self-exempted drugs.

The "King of Medicine" made a curtain call, and new drugs rose one after another.

Treatment strategies for autoimmune diseases include inflammation alleviation and immunosuppression. Although non-steroidal anti-inflammatory drugs, corticosteroids and anti-rheumatic drugs have good anti-inflammatory effects, they are difficult to fundamentally stop the development of the disease, and they are easy to relapse after stopping taking drugs. However, traditional non-selective immunosuppressants such as cyclosporine and methotrexate are not only slow to take effect, but also lead to a higher risk of cancer. As new immunosuppressants, bio-targeted drugs can selectively suppress the immune system, ensuring the safety while improving the curative effect, which is the most promising.

Hummel is a fully humanized monoclonal antibody against TNF-α developed by AbbVie Company, which was approved by FDA in 2002 for the treatment of rheumatoid arthritis. Because of its remarkable efficacy and safety in the treatment of self-immune diseases, Hummel’s indications have been expanding since its listing, and it has gradually become the highest-selling self-immune drug, and ranked first in global drug sales in 2012. Since then, through a series of marketing and patent strategies, AbbVie has made great efforts to extend the life cycle of Hummel, and promoted the drug to become the "drug king" in the world for ten consecutive years, with accumulated sales exceeding 200 billion US dollars since its listing.

With the official expiration of the patent in the United States in 2023, the market share of self-exempted drugs controlled by Hummel was quickly robbed by many similar biological drugs. According to AbbVie’s third quarterly report in 2023, nearly 10 biologically similar drugs have entered the market. As a result, the cumulative sales of Humele in the first three quarters of 2023 was only $11.1 billion, a sharp drop of 29.1% year-on-year. Nature Reviews Drug Discovery, a well-known medical journal, predicts that the annual sales of Hummel in 2023 will be about $13.6 billion, less than 60% of Keytruda of Top1, and the first generation of drug kings will soon "abdicate".

Corresponding to the curtain call of "King of Medicine", many innovative drugs with potential targets have risen rapidly, and a new generation of heavy drugs is coming out.

According to the global sales forecast of innovative drugs in 2023 recently released by Nature Review of Drug Discovery, the sales of self-immune biological agents Dupixent and Stelara, which target IL-4/IL-13 and IL-12/IL-23 respectively, have increased rapidly, and it is estimated that they will rank among the Top10 with sales of more than 10.6 billion US dollars.

Abbey, the owner of Hummel, is also actively looking for the next generation of self-free drugs. The sales amount of oral JAK1 inhibitor Rinvoq (upatinib) and IL-23 monoclonal antibody Skyrizi (risazhuzumab) under the company has increased rapidly in recent years. In 2022, the total sales revenue has exceeded 7 billion US dollars, and the growth rate is higher than 50%. Abbway predicts that by 2027, the combined sales revenue of these two drugs is expected to exceed the sales peak of Hummel’s $20 billion.

Domestic pharmaceutical companies compete for the next potential target.

Compared with the highly competitive innovative cancer drugs, the number of participants and innovative drugs in the self-exempt drug market is still relatively limited, and the overall market competition pattern is good. However, the huge unmet clinical needs and the continuous improvement of the diagnosis rate in China have also attracted more and more domestic innovative pharmaceutical companies to enter the drug-free track, and tried to gain a competitive advantage by virtue of differentiated layout potential targets and occupy a place in the domestic market.

So far, the targets of self-immune targeted drugs mainly focus on TNF-α, JAK, interleukin and BlyS, and the main indications are common rheumatoid arthritis, psoriasis, systemic lupus erythematosus and so on. Among them, targeted TNF-α drugs are the most classic targeted drugs for autoimmune diseases because of their early market time, mature targets and the widest range of indications. However, this track has basically been controlled by foreign-funded enterprises, and the development space of local manufacturers that follow is relatively limited. Domestic innovative drug companies have turned their research direction to JAK, interleukin and other targets.

Interleukin and its receptors are important target families in human immune regulation, and play an important role in various immune and inflammatory reactions. Psoriasis is the main indication of interleukin targeted drugs at present, and some targeted drugs have been proved to be safer than TNF-α antagonists in certain circumstances.

At present, the effective interleukin-targeting drugs listed in the world include tosilizumab targeting IL-6, ulinuzumab targeting IL-12/23, skukiyuzumab targeting IL-17A and gusechizumab targeting IL-23. Among domestic enterprises, Hengrui Pharma (600276.SH), Zhixiang Jintai (688443.SH) and Kangfang Bio (09926.HK) all have approved the listing of interleukin-targeted biological agents, and Quanxin Bio (01883.HK), Livzon Group (000513.SZ), Junshi Bio (688180.SH) and Cinda Bio.

JAK signaling pathway plays a very important role in autoimmune, tumor, hematological and other diseases, and it is one of the promising potential targets. Because the first generation of JAK inhibitors showed great toxic and side effects in the treatment process, the main research and development direction of major pharmaceutical companies is the second generation of JAK inhibitors targeting JAK1, JAK3, TYK2 and other targets with high specificity.

In clinical trials, the second generation JAK inhibitors have shown good data in terms of safety and efficacy. Among them, Upatinib, a JAK1 inhibitor listed by AbbVie, showed a better key remission index under the same safety in the head-to-head experiment of treating rheumatoid arthritis and adalimumab. In the first three quarters of 2023, the sales amount of Upatinib has reached US$ 2.71 billion, exceeding the annual performance in 2022. AbbVie expects that the drug is expected to achieve sales of more than $7.5 billion in 2025.

In view of the good performance of this target, the research on JAK-specific subunits has become one of the important directions of global innovative drug companies. Among domestic enterprises, Hengrui Pharma, Dizhe Medicine (688192.SH) and Nuocheng Jianhua (688428.SH) are in the top of the research and development progress. Among them, Nuocheng Jianhua recently disclosed that its TYK2 inhibitor ICP-488 under research has completed the first clinical administration for psoriasis patients in Phase II. ICP-332, another self-immune drug with the same target, disclosed the second phase clinical data of moderate and severe atopic dermatitis indications in December 2023. Orient securities believes that domestic JAK-targeted self-immune drugs are expected to achieve rapid volume increase after marketing through differentiated distribution of indications and optimized breakthrough in safety.

BlyS is one of the key factors in the differentiation and maturation of B lymphocytes, which is the most important effector cell of autoimmune diseases. By inhibiting BlyS, many autoimmune diseases can be treated. At present, there are two BlyS inhibitors on the market, namely, GlaxoSmithKline’s Beliyuzumab and Rongchang Bio (688331.SH)’ s Tatasip. The main indications are systemic lupus erythematosus, and the market structure is good.

Tetasip is an innovative drug of BLyS/APRIL dual-target fusion protein independently developed by Rongchang Bio. Clinical data show that the drug has the same level of efficacy and safety as Belizumab. In 2021, National Medical Products Administration conditionally approved Tatasip for the treatment of adult patients with systemic lupus erythematosus, and included it in the 2022 edition of the National Medical Insurance Catalogue; In November, 2023, the treatment of Tatasip in this indication was fully approved.

Rongchang Bio is also continuing to promote the clinical research on other indications of Tatasip, and the research on many indications such as rheumatoid arthritis, Sjogren’s syndrome and multiple sclerosis has entered the final clinical stage. In August, 2023, Tatasip was used to treat patients with rheumatoid arthritis in Phase III, and submitted an application for domestic marketing. On December 20th, the global multicenter Phase III clinical IND of Tatasip in the treatment of active primary Sjogren’s syndrome in adults was approved by the FDA of the United States, and clinical research will be carried out in many countries and regions around the world. The continuous enrichment of the clinical pipeline of Tetasip is expected to consolidate the innovative product matrix of the company and promote the continuous growth of the company’s income.

Take more than 200 million yuan to award the prize, and the result is "a Gree mobile phone"? Gree Electric: Free mobile phones have nothing to do with year-end awards.

Gree Electric vision china data map

Gree Electric’s extra year-end award of 200 million yuan is actually "a Gree G3 mobile phone for employees"?

On January 31, Gree Electric issued an official statement to clarify that the company was concerned about the false news circulating on the Internet, such as "On January 28, Chairman Dong Mingzhu said at the Gree 2024 Global Dream Festival that an extra year-end bonus of 200 million yuan was actually sent to Gree mobile phones".

Gree Electric mentioned two points in the statement: First, in order to better adapt to the company’s work software, facilitate mobile office work and improve work efficiency, the company decided to provide each employee with free work mobile phones (including free communication packages), which will be distributed in batches around the Spring Festival.

Second, the year-end bonus of 200 million yuan increased by the company has nothing to do with the free work mobile phone. The scope of the increased year-end bonus does not include middle and senior cadres, and the increased part is inclined to the front-line employees.

Gree Electric said that the company reserves the right to investigate the legal responsibility of media and individuals who spread rumors and rumors according to law.

Previously, a related person in Gree Electric said, "Fake, nonsense."

On January 28th, Dong Mingzhu, Chairman and President of Gree Electric, said at the Gree 2024 Global Dream Festival that her performance reached a new high last year, creating a profit of 29 billion yuan. At the same time, she also announced that she would "give employees an extra 200 million yuan for the year-end bonus".

However, while Gree Electric’s heroic 200 million year-end bonus has aroused widespread concern, there are also questions about this year-end bonus on the Internet.

On January 30th, there were rumors on the Internet that the 200 million year-end bonus was actually "one Gree G3 mobile phone for each person" and "giving employees more G3 mobile phones with a value of 200 million". Moreover, these G3 mobile phones "can’t be sold at the price of idle fish only around 300 yuan, but the company has issued 80,000 sets at a price of 3,599 yuan".

For these rumors, Gree Electric insiders told the media: "The fake, extra 200 million bonus is not deducted by G3 mobile phone, but a real year-end bonus."

Regarding the rumor that "Gree’s year-end award is deducted with points", Gree also said that "the year-end award is not issued in the form of points".

On the short video platform, some Gree Electric employees have already got their own year-end awards, which are divided into two parts: cash+points for products. The employee of Gree Electric’s subsidiary got a year-end bonus of 4,500 yuan in cash, and also exchanged the points for products such as rice cookers, health pots and electric fans, with a value of about 4,000 yuan.

At the Gree 2024 Global Dream Festival, Dong Mingzhu said that 2023 was the best year for Gree Electric since its founding 33 years ago, and the corporate tax revenue reached a record high. This achievement can not be separated from the hard work of every employee and the teamwork spirit.

Dong Mingzhu said that in order to let employees fully enjoy the fruits of the company’s development, he decided to give employees an extra 200 million yuan for the year-end bonus. At the same time, Dong Mingzhu also expressed the hope that the tax revenue for the country will exceed 20 billion in 2024.

Dong Mingzhu also said that Gree Electric doesn’t care about the stock price, because it doesn’t depend on the stock price to survive.

Previously, the performance forecast released by Gree Electric showed that the total operating income in 2023 is expected to be between 205 billion yuan and 210 billion yuan, up by 7.8% to 10.4% year-on-year; It is estimated that the net profit attributable to shareholders of the parent company will be between 27 billion yuan and 29.3 billion yuan, up 10.2% to 19.6% year-on-year; It is estimated that the net profit attributable to shareholders of the parent company after deducting non-recurring gains and losses will be between 26.1 billion yuan and 27.8 billion yuan, up 8.8% to 15.9% year-on-year.

As of January 31st, Gree Electric rose 0.28% to close at 35.25 yuan.

State Post Bureau: On the day of "double 11", the country handled 535 million express mail.

Data map: Taiyuan, Shanxi, postal workers are sorting express delivery. China News Service reporter Zhang Yunshe

  BEIJING, Nov. 12 (Xinhua) According to the official WeChat news of the State Post Bureau, on November 11, according to the monitoring data of the State Post Bureau, postal and express delivery companies handled 535 million express mail all day, which was three times the daily processing volume since the second quarter, with a year-on-year increase of 28.6%, a record high.

  It is estimated that the peak season of "double 11" this year will last from November 11th to 18th. During the peak period, the whole industry will handle 2.8 billion pieces of express mail. The whole industry still regards "peak-shifting delivery and balanced promotion" as the core mechanism, and strictly controls the peak delivery volume according to the delivery carrying capacity of each enterprise and the planned push volume. Through big data platforms such as postal industry safety supervision information system and e-commerce collaborative platform, the State Post Bureau will pay close attention to the whole network operation in real time, guide enterprises to control the dispatching rhythm, and moderately extend the delivery time limit of double 11.

  In order to achieve the goals of "two noes" (no paralysis of the whole network and no explosion of important nodes) and "three guarantees" (smooth flow, safety and stability), on the basis of the existing service capacity, the whole industry temporarily hired nearly 400,000 people and 120,000 vehicles, and added more than 3.6 million square meters of processing sites and more than 3,000 sets of automatic and semi-automatic sorting equipment. Technically, unmanned warehouses, drones and unmanned vehicles have gradually achieved mass production and large-scale application. More than 200 intelligent distribution centers have been built nationwide, and many unmanned warehouses have been set up by enterprises such as SF, JD.COM, Cainiao and Suning. A large number of heavy-duty storage robots and distribution robots have been promoted and applied in different occasions, and the "illegal operation AI intelligent identification system" that automatically identifies violent sorting behavior has been put into operation in some enterprises. In urban areas, 82,000 terminal public service stations have been built nationwide, and more than 380,000 sets of intelligent express boxes have been deployed, effectively supplementing the terminal service capacity of express delivery. The establishment of 59,000 rural express public pick-up and delivery points will better meet the delivery service needs of rural residents. In terms of international business, the outlets of express delivery enterprises in more than 60 countries, overseas warehouses covering more than 50 countries and regions and new international routes will play a very positive role. In terms of after-sales, AI intelligent customer service robots that can achieve 24-hour service have been put into use in many enterprises, which will effectively improve customer service capacity during peak hours.

  In response to the consumer’s concern about the "last mile" in rural areas in the peak season, the relevant person in charge of the State Post Bureau pointed out that up to now, express outlets have covered more than 30,000 towns and villages, and the coverage rate of express outlets in towns and villages nationwide has reached 96%, effectively improving the distribution capacity in rural areas. At the same time, the State Post Bureau specially issued the "Implementation Plan for Accelerating Express Delivery to the Countryside" this year, intensified efforts to build a terminal delivery service system consisting of home delivery, box delivery and platform delivery, and constantly promoted the integrated development of transportation and postal express delivery, and promoted the coordinated development of express delivery and rural e-commerce. In addition, since April this year, two rounds of cleaning up and rectifying illegal charges for express terminal services have been deployed nationwide, effectively safeguarding the legitimate rights and interests of farmers. On the issue of express packaging, with the help of "double 11", the industry has vigorously promoted the "9571" project of green development, continuously reduced the secondary packaging of e-commerce express mail, and deployed 27,000 standardized express packaging recycling devices at terminal service stations. At the same time, enterprises have done a lot of work in reducing the use of packaging materials, promoting electronic face sheets, circulating transfer bags and packaging recycling boxes.