Bright picture

　　[educational perspective]

　　The epidemic has caused many inconveniences in finding jobs.

　　For most college students who will graduate in 2020, COVID-19, an unfamiliar word, will be engraved in their memories along with their tortuous job hunting experience. Because of the development of the epidemic in COVID-19, in order to protect students’ health and life safety and prevent the spread of the epidemic, the national education administrative departments and universities have taken emergency measures to limit the flow of personnel, and all kinds of campus recruitment activities have been suspended.

　　According to the practice of previous years, the coming March and April was originally the peak period for fresh college students to apply for jobs and sign contracts, but because of the epidemic, the employment and recruitment activities of college students were silent this spring.

　　The superposition of all these unfavorable factors undoubtedly affects the job selection of college graduates and the selection of talents by employers, which invisibly increases the pressure of college students’ employment.

　　For China’s economic development, the impact of the COVID-19 epidemic on the economy is bound to have a chain reaction, which will be transmitted and reflected in the employment sector — — Not only the temporary communication difficulties between graduates and enterprises and the inability to carry out recruitment activities, but also the demand for employers may be reduced. Of course, some industry sectors, such as medical and health care, environmental engineering, chemical technology and other employment needs are likely to increase.

　　The interview and employment pressure of job-seeking students has increased sharply. The silence in March and April, the peak of job hunting, dealt a heavy blow to college students’ employment signing. Because some students and employers have drawn up their initial intentions and need to go to the employer for an interview, but now the unit can’t operate normally, students can’t go out, and the recruitment and interview plans of some companies have also changed, and students are in a dilemma.

　　Stuck by the time limit, students who are pursuing further studies are in a dilemma. The postponement of the re-examination of the postgraduate entrance examination has a great influence on students. The uncertainty of whether they can pass the initial examination and whether they can be admitted after the re-examination makes most postgraduate students anxious, fearing that they may miss favorable employment opportunities after falling out of the list.

　　At the same time, taking into account epidemic prevention and employment, colleges and universities are facing multiple tests. Up to now, due to the pressure of economic adjustment, the employment rate of graduates who originally signed up to implement employment units is not optimistic. The arrival of the epidemic has made colleges and universities more pressure on epidemic prevention and teaching adjustment under the new situation than before, and the pressure on subsequent employment guidance has undoubtedly increased accordingly. The impact and impact of these pressures on local colleges and universities with the majority of local students will be less than those with scattered students’ origin and employment destination.

　　To cope with the pressure of employment, take many measures to promote Qi Li.

　　Employment must be promoted by the government, universities, employment enterprises and units, giving full play to their respective advantages in resources, channels and experience. As for the universities directly facing the above employment pressure, how to deal with this year’s new situation?

　　Colleges and universities should not panic when they serve college students’ employment under pressure.At present, we can see that under the decisive and correct decision-making and leadership of the CPC Central Committee, the understanding of COVID-19 has gradually deepened, and the fight against the epidemic has achieved initial results. The confirmed cases and suspected cases in high-incidence areas have been running at a low level, and the epidemic situation in most areas has been effectively controlled. I believe that with the support and encouragement of various supporting policies of the state, all economic construction activities will be carried out in an orderly manner. This is the biggest good news for economic activities directly related to employment.

　　College students start job hunting and employment rationally and calmly.Then, after the epidemic is controlled, the employment activities of college students that have been temporarily suspended will be restarted, and the suppressed demand for employment will be released again. Therefore, for colleges and graduates, they should gradually become rational, sober and brave from the initial panic, anxiety and sorrow, and there is no need to panic at all. They should have full confidence and calmly and objectively carry out the employment work during the epidemic period according to the arrangement of the national education administrative department.

　　Enterprises should promptly strengthen the organization of online employment recruitment activities.Before the epidemic has been completely controlled, in order to prevent large-scale gathering of people, the on-site recruitment activities of various college graduates have been suspended. In this case, colleges and universities should vigorously promote the development of online employment activities, and guide more enterprises to organize more online recruitment activities in a planned way to provide graduates with job opportunities; Students can get job information and enjoy online employment services by browsing national and provincial employment platforms, university employment networks and social recruitment websites.

　　Multi-party cooperation to explore innovative employment channels.Colleges and universities should take the initiative to coordinate relevant parties and further organize and implement grassroots projects such as the special post teacher plan, the university student village official, the three supports and one support, and the university student volunteer service plan for the western region; Encourage college students to join the army and serve national defense; Further implement preferential policies such as tuition subsidy for grassroots employment and encourage graduates to work and start businesses at the grassroots level; Establish a docking platform for school-enterprise cooperation and strengthen the docking of talent supply and demand in key areas, major projects, major projects and important fields; Further explore the employment opportunities created by the deep integration of the Internet, big data, artificial intelligence and the real economy, and support graduates to achieve multi-channel employment; Call on employers to hold campus job fairs, take recruitment tests exams, receive graduates’ resumes and practice training through the Internet and other more flexible ways.

　　Focus on strengthening the focus on helping students from difficult families.Colleges and universities must actively design and provide one-on-one assistance to poor family graduates, physically disabled graduates and other groups, and carry out targeted job promotion. It is urgent to form a team of relevant university leaders, fully grasp the latest trends of students, regional economy and professional fields, open a hotline for employment consultation and help, and develop a number of online employment guidance courses to do a good job in promoting graduates’ employment, enterprise docking and psychological counseling.

　　The epidemic will eventually pass. As long as all parties face it confidently, calmly, optimistically and scientifically, with the overall victory in the fight against the epidemic, the employment situation of college graduates in 2020 will certainly improve and usher in "spring"!

　　 (Author: Zong Cheng, a postdoctoral fellow at China Academy of Educational Sciences)

The 2023 Dodge Ram Tyrannosaurus Rex in Tianjin Port is now sold in the sixth country, and it is licensed nationwide. The 23 Dodge Ram Tyrannosaurus Rex uses a supercharged 6.2-liter HEMI? HELLCAT V8 engine with a maximum horsepower of 712 horsepower and a maximum torque of 881 Nm. Ram 1500 TRX has become the fastest and most powerful mass-produced half-ton pickup truck in the world. In terms of torque, TRX provides a new performance level with a speed of 0 to 100 km/h in 4.9 seconds and a top speed of 190 km/h.

　　

Configuration: limited edition of TRX ignition (MoparTRX ignition decal, TRX special edition central control logo, 18-inch wheels, orange decorative stitching, pedestrian emergency braking, leather and carbon flat-bottomed steering wheel, carbon fiber interior, Mopar container telescopic pedal, Mopar4-way adjustable cargo binding hook, adaptive cruise with start and stop, double-window panoramic sunroof, lane keeping aid, and bottom two-color car paint. Mopar embedded container liner) TRX 2 package (leather trimmed bucket seat, front seat ventilation, wrapped main driver’s assistant armrest, luxurious front door panel decoration, full-length advanced upgraded center console, lift display, digital rearview mirror, advanced wrapped instrument panel, LED ambient light, radio/main driver’s seat/mirror/pedal memory function, main driver’s seat memory, 4-way electric lumbar support passenger seat, 8-way electric main driver and passenger. Electric adjustable pedal includes memory function, pedal lighting, traction braking management, Harman Kardon advanced audio includes 19 speakers, blind spot and intersection detection, front seat heating, second seat heating, steering wheel heating, parking assistance before and after parking induction includes stop function, cargo box lighting, rain sensing front windshield wiper, rear seat bottom storage box, electric tailgate, rear 60/40 folding seat, Mopar cross-country style pedal, and traction reverse steering control.

The exterior design of the Dodge Ram Tyrannosaurus Rex has a strong sense of impact. Compared with the well-behaved family design, the front of the Dodge Ram Tyrannosaurus Rex is undoubtedly a little more aggressive to the road. The eyes do not reveal a trace of lively charm, and the only thing that is displayed is fierceness. The front bumper is an iron front bumper with a hook, which exudes a metallic atmosphere and is calm and atmospheric. As the best-selling model, it has a very aggressive front face. Dodge Ram Tyrannosaurus Rex has completely got rid of the rough feeling of the United States. The edges and seams are carefully handled. The leather seats are independent and equipped with comfortable functions such as heating and massage. Each seat is equipped with a control handle independently, and each function is controlled by the rider himself. All seats of Dodge Ram pickup truck are wrapped in leather, and the front row is also equipped with very practical sports seats.

　The design of the 2023 Dodge Ram Tyrannosaurus Rex center console is simple and hard, which conforms to the temperament of the ram. The bottom of the dashboard has patterns, which further highlights the elegance of this car. The soft instrument panel design is very comfortable to the touch, and there is nothing stiff.

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The chassis of 23 Dodge Tyrannosaurus Rex has also been greatly upgraded. The chassis is made of a large number of high-strength steel to improve the rigidity of the frame. At the same time, the suspension system is also equipped with an adaptive shock absorber from Bilstein, which can reduce the vibration during high-speed desert driving and off-road, and improve driving performance and durability.

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The interior of the 23 Dodge Tyrannosaurus Rex is simple and generous, but this will not affect its luxurious texture. The rich configuration will make you admire it. At the same time, as the flagship model of the Dodge family, the new car is also equipped with a 12-inch vertical central control screen. In addition to supporting common functions such as Bluetooth, navigation and car Wi-Fi, it also supports Apple CarPlay and Android Auto phones.

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In addition to its powerful power, the performance version of the 23 Dodge Ram Tyrannosaurus Rex is also first-class in off-road performance. The clearance between the vehicle and the floor is 28cm, the contact angle is 30.2, the departure angle is 23.5, the passing angle is 21.9, and the wading height is 81.28cm, which can correspond to most sections. In addition, the new car is equipped with an adaptive shock absorber from Bilstein, and the stroke of the front and rear wheels reaches 33.

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Special feature of 1905 film network When the opera meets the film, since its release, it has been evaluated with the high score of Douban 8.2 by virtue of the audience’s good reputation.

As the first 4K panoramic Cantonese opera film, it was shortlisted for the best opera film in the Golden Rooster Award for Chinese films, and also won the Golden Coconut Award for the best technology in Hainan Island International Film Festival. Through film technology, traditional Chinese opera is given a new look, and behind this, it is also inseparable from the credit of editing technology.

The editor of this film is a national first-class editor. His previous representative works include Youth Fight, Deep Sea Sword and Men’s Gang. Sun Yiqun’s mother is also an editor. She is Yang Xingyuan, the former president of China Film Editing Society, and her representative editing works are various.

Can editing technology be inherited? In this issue of Behind the Scene, Yang Xingyuan and Sun Yiqun, the editors, lead us into china national film museum to reveal the history of film film editing, and experience the technological changes of film editing together from the film age to the digital age.

Behind the scenes: Film editor Yang Xingyuan reveals the tools of "film film editing"

Film clip: "Manual sewing machine"

I have a particularly cordial feeling. I can feel the temperature of all these devices. Entering china national film museum, Yang Xingyuan knows a lot about the film editing machines in the museum.

　

Facing a splicing machine full of historical colors, Yang Xingyuan introduced that Premier Zhou Enlai cared about film splicing and specially entrusted Tianjin No.2 Optical Instrument Factory to develop this splicing machine for them, also known as the four-way sound painting machine.

From the end of the 1960s to the end of the 1990s, this was the only tool for their editors, and the frequency was controlled in the frequency of 24 squares by hand. "My editing of Man to Middle Age, Zhou Enlai and Armageddon was cut out by such a machine."

The process of film editing is particularly complicated. After the film is finished, it should be washed in the studio, and then printed into samples with the negative, and the editor and the director and other producers will jointly review it.

　

When editing, the sound and picture of the sample should be synchronized with the negative, so the first step of editing is not to cut, but to arrange, and each of the specific scenes, shots and sound tapes in all the shooting materials should be completely recorded first, otherwise the material synchronized with the negative can not be found later.

　

"So it’s not easy to start editing. All this work has to be done before you can enter the creative stage." Yang Xingyuan said that it is more difficult at the stage of revision. For example, if there are ten films and one place is revised, these ten films will have to be hand-cranked from beginning to end on the film receiver. "After shaking it down, it is a lot of films, and then it is lifted one by one. At that time, the state positioned the editor as a light manual worker. "

Recalling the editing work of "Zhou Enlai", at that time, the version of mixed editing of picture and sound was completed, but the director had to modify the picture temporarily. "I was so angry that I wouldn’t change it for you, but he personally took a dozen films upstairs and asked me to change it." In order to make the film better, Yang Xingyuan said that even if the editing process was not easy at that time, it still had to be modified.

In the past, when editing technology was underdeveloped, a small machine supported the creation of many excellent classic films. Sun Yiqun recalled, "At that time, my mother stayed up late at night, so I slept next to her with a small quilt. I always wanted to shake this film, and my mother was particularly afraid that I would destroy it. She said that if you broke it, the consequences would be unimaginable."

Nowadays, computer technology is very simple to operate the effects of transition editing, such as fade-in, fade-out, cut-in and cut-out, overlapping, etc., but it is very troublesome in the film age. It is necessary for the editor to make specific marks on the film with a special pen, and then let the special effects producers use optical skills to make them on the film.

　

The complicated and exquisite technology of film film editors bears the heavy history of China films.

"For example, there are seven kinds of scenes to record a dialogue and an action now. I think the workload is very heavy. There are more than 200 shots as soon as I open the folder, but it is much more complicated than us to hear these things that the predecessors are editing. My mother sewed by hand at that time, and now it is equivalent to using an electric sewing machine. "

　

Hearing his mother’s introduction to film editing technology, Sun Yiqun felt a lot. "Now we have mastered new technologies and brought us convenience, while the older generation got through it like that and admired it."

Digital editing: White Snake’s secret recipe

The era of film editing has ended, and digital computer technology has been fully popularized. Nowadays, Sun Yiqun’s editing work is no longer just a simple operation technology, but also needs to integrate his own ideas at the creative level.

　

Talking about her latest film White Snake, Sun Yiqun said that in editing skills, she paid special attention to the balance between drama and film.

"There are many stylized things in traditional Chinese opera. Actors often communicate with the audience and the camera, which breaks the spatial illusion that the film has carefully established." Therefore, she will especially avoid editing the lens that highlights the "fourth wall" and choose more pictures of actors communicating with each other.

　

When the traditional Chinese opera performance is put on the movie screen, it is easy to have a magnifying effect. In addition, it is 4K quality, and any tiny expression of the actor can be clearly captured. When editing, Sun Yiqun will also avoid the scenes that will appear exaggerated on the big screen.

"The hand, eye, body and steps of an opera actor, his figure is a very important aspect of expression. If I edit excessively or even choose inappropriate scenery, it will destroy the good rhythm of the opera, so I still have to pick up its rhythm and grasp it well." How to find a moderate point is a difficult part of this editing.

　

Sun Yiqun is also worried that if the aria is too long, it will affect the audience’s desire to watch. Among them, there is a scene of "Broken Bridge and Residual Snow", in which lady white snake complains to Xu Xian after suffering, and the recorded aria is very long. She took the initiative to discuss the reduction with the director. "Otherwise, it would ruin lady white snake’s image and become a dissatisfied housewife." Finally, after coordination and careful cutting, it was cut for more than 30 minutes.

White Snake reinterprets classic stories and boldly tries new editing techniques of combining drama with film. Yang Xingyuan feels that today’s editors have a higher pursuit than the older generation. "They need to have the ability to master the lens and handle the structure, not the things we have learned. Those things have passed. They can put more energy into creation. "

Two generations of editing methods

Yang Xingyuan was originally an actor, but later transferred to Changying and changed to editing. "Having been an actor for more than ten or twenty years, I can still understand the performance and rhythm, and this accumulation will be useful. I just thought I could learn to edit and play my little role."

　

Thanks to her experience as an actor, Yang Xingyuan switched to editing, and she can better handle the rhythm of performances and shots.

　

When cutting "Man to Middle Age", because Lu Wenting and Yang Xingyuan are both of the same generation, Yang Xingyuan said that she edited the character completely according to the character and her own feelings. "Lu Wenting went to see the child, and the editor must understand how she looked at it in order to impress the audience. So I chose her to post it in the nearest place to watch the child sleeping, so that I can understand the psychological feelings of this character. "

With more than 40 years of experience in behind-the-scenes editing, Yang Xingyuan concluded that editors should think about editing from three angles.

　

The first is the director. "I must know what he wants to do, what he wants to show and what he wants to give to the audience." Then there is the character, "to understand the character’s mentality and his various things."

Then there is the audience. "You must know what the audience wants to see and where his interest lies. I can’t say that I am an old lady now. My rhythm is slow, so I don’t appreciate the audience’s appreciation ability. I also deal with the film according to my rhythm and speed, and the audience will definitely stop watching it. "

Daughter Sun Yiqun did a lot of work that had nothing to do with art. Later, her mother thought she should learn a skill, so she taught her to edit and took her into the business. The two later jointly edited the TV series Behind the Vanity.

　

"They always ask why the play they cut is not good-looking. I said that because you cut the process, it is not a play." Sun Yiqun believes that a good editing is to "pick up" the scene and find the eye of the scene, while a bad editing is to exert an average force. "If the scene and the scene are not more energetic, it will not work."

　

In her view, editing and scriptwriting have a lot in common, they all want to tell stories, and they all want to think about how to make this story vivid, interesting and arresting.

From Yang Xingyuan to Sun Yiqun, from film editing to digital editing, the editors of mother and daughter have great enthusiasm for this art, which has been passed down from generation to generation not only for the iterative upgrade of film editing skills, but also for the consistent dedication, concentration, lean and innovative craftsmanship as editors.

The year 2023 is of great significance to the drugs for autoimmune diseases and even to the global innovative drug market. With the expiration of patents in key markets, Hummel (adalimumab) will officially hand over the title of global sales champion for 11 years, and the first generation of "drug king" will officially end.

Due to the complex pathogenesis, the number of patients with autoimmune diseases is large and it is difficult to cure. The long-term or even lifelong demand for drugs has spawned a huge market for autoimmune drugs, which has become a hotbed for the growth of heavy drugs.

Under the demonstration effect of "drug king", major pharmaceutical companies around the world have been scrambling for layout in recent years. At present, breakthroughs have been made in the development of new drugs for potential targets such as JAK and interleukin, and the free drug track is expected to usher in a new round of competition. Local innovative drug companies try to gain a place in the domestic free drug market through differentiated distribution of indications and continuous optimization of safety.

The market for self-exempted drugs continues to grow steadily.

Autoimmune system diseases refer to diseases caused by immune response to autoantigens and self-tissue damage. Genetic defects and environmental factors are all important links in inducing autoimmune diseases. The complex disease mechanism leads to a wide variety of autoimmune diseases and a large patient base. At present, there are more than 100 known main disease types, including psoriasis, atopic dermatitis, compulsory spondylitis, rheumatoid arthritis and systemic lupus erythematosus.

As a chronic disease, autoimmune diseases usually do not directly kill people, but it is also difficult to cure them. Such as compulsory spondylitis, systemic lupus erythematosus, etc., once suffering from it, it will be difficult to reverse, which is called "undead cancer". Patients need long-term or even lifelong medication, thus giving birth to the long-term and stable growth of market demand for self-immune drugs.

Based on the financial report data of major pharmaceutical companies, in 2022, there were 22 self-disease-free drugs in the list of TOP100 drugs with global sales scale, of which 10 drugs exceeded $3 billion and the total sales exceeded $70 billion.

According to the statistics of AARDA, patients with autoimmune diseases account for 7.6%-9.4% of the global population in recent years. Jost Sullivan’s statistics show that there are nearly 500 million patients with various kinds of self-immune diseases in the world, and the global self-immune drug market will reach about 132.3 billion US dollars in 2022, which has become the second largest disease market after cancer.

Jost Sullivan predicted that by 2030, the global self-exempted drug market is expected to reach US$ 176 billion, with a compound annual growth rate of 3.6% from 2022 to 2030. Among them, the self-exempted drug market in China is expected to reach nearly US$ 25 billion in 2030, a tenfold increase compared with 2020, which is an important incremental source of global self-exempted drugs.

The "King of Medicine" made a curtain call, and new drugs rose one after another.

Treatment strategies for autoimmune diseases include inflammation alleviation and immunosuppression. Although non-steroidal anti-inflammatory drugs, corticosteroids and anti-rheumatic drugs have good anti-inflammatory effects, they are difficult to fundamentally stop the development of the disease, and they are easy to relapse after stopping taking drugs. However, traditional non-selective immunosuppressants such as cyclosporine and methotrexate are not only slow to take effect, but also lead to a higher risk of cancer. As new immunosuppressants, bio-targeted drugs can selectively suppress the immune system, ensuring the safety while improving the curative effect, which is the most promising.

Hummel is a fully humanized monoclonal antibody against TNF-α developed by AbbVie Company, which was approved by FDA in 2002 for the treatment of rheumatoid arthritis. Because of its remarkable efficacy and safety in the treatment of self-immune diseases, Hummel’s indications have been expanding since its listing, and it has gradually become the highest-selling self-immune drug, and ranked first in global drug sales in 2012. Since then, through a series of marketing and patent strategies, AbbVie has made great efforts to extend the life cycle of Hummel, and promoted the drug to become the "drug king" in the world for ten consecutive years, with accumulated sales exceeding 200 billion US dollars since its listing.

With the official expiration of the patent in the United States in 2023, the market share of self-exempted drugs controlled by Hummel was quickly robbed by many similar biological drugs. According to AbbVie’s third quarterly report in 2023, nearly 10 biologically similar drugs have entered the market. As a result, the cumulative sales of Humele in the first three quarters of 2023 was only $11.1 billion, a sharp drop of 29.1% year-on-year. Nature Reviews Drug Discovery, a well-known medical journal, predicts that the annual sales of Hummel in 2023 will be about $13.6 billion, less than 60% of Keytruda of Top1, and the first generation of drug kings will soon "abdicate".

Corresponding to the curtain call of "King of Medicine", many innovative drugs with potential targets have risen rapidly, and a new generation of heavy drugs is coming out.

According to the global sales forecast of innovative drugs in 2023 recently released by Nature Review of Drug Discovery, the sales of self-immune biological agents Dupixent and Stelara, which target IL-4/IL-13 and IL-12/IL-23 respectively, have increased rapidly, and it is estimated that they will rank among the Top10 with sales of more than 10.6 billion US dollars.

Abbey, the owner of Hummel, is also actively looking for the next generation of self-free drugs. The sales amount of oral JAK1 inhibitor Rinvoq (upatinib) and IL-23 monoclonal antibody Skyrizi (risazhuzumab) under the company has increased rapidly in recent years. In 2022, the total sales revenue has exceeded 7 billion US dollars, and the growth rate is higher than 50%. Abbway predicts that by 2027, the combined sales revenue of these two drugs is expected to exceed the sales peak of Hummel’s $20 billion.

Domestic pharmaceutical companies compete for the next potential target.

Compared with the highly competitive innovative cancer drugs, the number of participants and innovative drugs in the self-exempt drug market is still relatively limited, and the overall market competition pattern is good. However, the huge unmet clinical needs and the continuous improvement of the diagnosis rate in China have also attracted more and more domestic innovative pharmaceutical companies to enter the drug-free track, and tried to gain a competitive advantage by virtue of differentiated layout potential targets and occupy a place in the domestic market.

So far, the targets of self-immune targeted drugs mainly focus on TNF-α, JAK, interleukin and BlyS, and the main indications are common rheumatoid arthritis, psoriasis, systemic lupus erythematosus and so on. Among them, targeted TNF-α drugs are the most classic targeted drugs for autoimmune diseases because of their early market time, mature targets and the widest range of indications. However, this track has basically been controlled by foreign-funded enterprises, and the development space of local manufacturers that follow is relatively limited. Domestic innovative drug companies have turned their research direction to JAK, interleukin and other targets.

Interleukin and its receptors are important target families in human immune regulation, and play an important role in various immune and inflammatory reactions. Psoriasis is the main indication of interleukin targeted drugs at present, and some targeted drugs have been proved to be safer than TNF-α antagonists in certain circumstances.

At present, the effective interleukin-targeting drugs listed in the world include tosilizumab targeting IL-6, ulinuzumab targeting IL-12/23, skukiyuzumab targeting IL-17A and gusechizumab targeting IL-23. Among domestic enterprises, Hengrui Pharma (600276.SH), Zhixiang Jintai (688443.SH) and Kangfang Bio (09926.HK) all have approved the listing of interleukin-targeted biological agents, and Quanxin Bio (01883.HK), Livzon Group (000513.SZ), Junshi Bio (688180.SH) and Cinda Bio.

JAK signaling pathway plays a very important role in autoimmune, tumor, hematological and other diseases, and it is one of the promising potential targets. Because the first generation of JAK inhibitors showed great toxic and side effects in the treatment process, the main research and development direction of major pharmaceutical companies is the second generation of JAK inhibitors targeting JAK1, JAK3, TYK2 and other targets with high specificity.

In clinical trials, the second generation JAK inhibitors have shown good data in terms of safety and efficacy. Among them, Upatinib, a JAK1 inhibitor listed by AbbVie, showed a better key remission index under the same safety in the head-to-head experiment of treating rheumatoid arthritis and adalimumab. In the first three quarters of 2023, the sales amount of Upatinib has reached US$ 2.71 billion, exceeding the annual performance in 2022. AbbVie expects that the drug is expected to achieve sales of more than $7.5 billion in 2025.

In view of the good performance of this target, the research on JAK-specific subunits has become one of the important directions of global innovative drug companies. Among domestic enterprises, Hengrui Pharma, Dizhe Medicine (688192.SH) and Nuocheng Jianhua (688428.SH) are in the top of the research and development progress. Among them, Nuocheng Jianhua recently disclosed that its TYK2 inhibitor ICP-488 under research has completed the first clinical administration for psoriasis patients in Phase II. ICP-332, another self-immune drug with the same target, disclosed the second phase clinical data of moderate and severe atopic dermatitis indications in December 2023. Orient securities believes that domestic JAK-targeted self-immune drugs are expected to achieve rapid volume increase after marketing through differentiated distribution of indications and optimized breakthrough in safety.

BlyS is one of the key factors in the differentiation and maturation of B lymphocytes, which is the most important effector cell of autoimmune diseases. By inhibiting BlyS, many autoimmune diseases can be treated. At present, there are two BlyS inhibitors on the market, namely, GlaxoSmithKline’s Beliyuzumab and Rongchang Bio (688331.SH)’ s Tatasip. The main indications are systemic lupus erythematosus, and the market structure is good.

Tetasip is an innovative drug of BLyS/APRIL dual-target fusion protein independently developed by Rongchang Bio. Clinical data show that the drug has the same level of efficacy and safety as Belizumab. In 2021, National Medical Products Administration conditionally approved Tatasip for the treatment of adult patients with systemic lupus erythematosus, and included it in the 2022 edition of the National Medical Insurance Catalogue; In November, 2023, the treatment of Tatasip in this indication was fully approved.

Rongchang Bio is also continuing to promote the clinical research on other indications of Tatasip, and the research on many indications such as rheumatoid arthritis, Sjogren’s syndrome and multiple sclerosis has entered the final clinical stage. In August, 2023, Tatasip was used to treat patients with rheumatoid arthritis in Phase III, and submitted an application for domestic marketing. On December 20th, the global multicenter Phase III clinical IND of Tatasip in the treatment of active primary Sjogren’s syndrome in adults was approved by the FDA of the United States, and clinical research will be carried out in many countries and regions around the world. The continuous enrichment of the clinical pipeline of Tetasip is expected to consolidate the innovative product matrix of the company and promote the continuous growth of the company’s income.

Gree Electric vision china data map

Gree Electric’s extra year-end award of 200 million yuan is actually "a Gree G3 mobile phone for employees"?

On January 31, Gree Electric issued an official statement to clarify that the company was concerned about the false news circulating on the Internet, such as "On January 28, Chairman Dong Mingzhu said at the Gree 2024 Global Dream Festival that an extra year-end bonus of 200 million yuan was actually sent to Gree mobile phones".

Gree Electric mentioned two points in the statement: First, in order to better adapt to the company’s work software, facilitate mobile office work and improve work efficiency, the company decided to provide each employee with free work mobile phones (including free communication packages), which will be distributed in batches around the Spring Festival.

Second, the year-end bonus of 200 million yuan increased by the company has nothing to do with the free work mobile phone. The scope of the increased year-end bonus does not include middle and senior cadres, and the increased part is inclined to the front-line employees.

Gree Electric said that the company reserves the right to investigate the legal responsibility of media and individuals who spread rumors and rumors according to law.

Previously, a related person in Gree Electric said, "Fake, nonsense."

On January 28th, Dong Mingzhu, Chairman and President of Gree Electric, said at the Gree 2024 Global Dream Festival that her performance reached a new high last year, creating a profit of 29 billion yuan. At the same time, she also announced that she would "give employees an extra 200 million yuan for the year-end bonus".

However, while Gree Electric’s heroic 200 million year-end bonus has aroused widespread concern, there are also questions about this year-end bonus on the Internet.

On January 30th, there were rumors on the Internet that the 200 million year-end bonus was actually "one Gree G3 mobile phone for each person" and "giving employees more G3 mobile phones with a value of 200 million". Moreover, these G3 mobile phones "can’t be sold at the price of idle fish only around 300 yuan, but the company has issued 80,000 sets at a price of 3,599 yuan".

For these rumors, Gree Electric insiders told the media: "The fake, extra 200 million bonus is not deducted by G3 mobile phone, but a real year-end bonus."

Regarding the rumor that "Gree’s year-end award is deducted with points", Gree also said that "the year-end award is not issued in the form of points".

On the short video platform, some Gree Electric employees have already got their own year-end awards, which are divided into two parts: cash+points for products. The employee of Gree Electric’s subsidiary got a year-end bonus of 4,500 yuan in cash, and also exchanged the points for products such as rice cookers, health pots and electric fans, with a value of about 4,000 yuan.

At the Gree 2024 Global Dream Festival, Dong Mingzhu said that 2023 was the best year for Gree Electric since its founding 33 years ago, and the corporate tax revenue reached a record high. This achievement can not be separated from the hard work of every employee and the teamwork spirit.

Dong Mingzhu said that in order to let employees fully enjoy the fruits of the company’s development, he decided to give employees an extra 200 million yuan for the year-end bonus. At the same time, Dong Mingzhu also expressed the hope that the tax revenue for the country will exceed 20 billion in 2024.

Dong Mingzhu also said that Gree Electric doesn’t care about the stock price, because it doesn’t depend on the stock price to survive.

Previously, the performance forecast released by Gree Electric showed that the total operating income in 2023 is expected to be between 205 billion yuan and 210 billion yuan, up by 7.8% to 10.4% year-on-year; It is estimated that the net profit attributable to shareholders of the parent company will be between 27 billion yuan and 29.3 billion yuan, up 10.2% to 19.6% year-on-year; It is estimated that the net profit attributable to shareholders of the parent company after deducting non-recurring gains and losses will be between 26.1 billion yuan and 27.8 billion yuan, up 8.8% to 15.9% year-on-year.

As of January 31st, Gree Electric rose 0.28% to close at 35.25 yuan.

Image source: China Radio Network

CCTV News:"Family, less idle month, people twice as busy in June. At night, the south wind rises and the wheat is covered with yellow. " It’s the wheat harvest season in a year. Under the blue sky in the distance, golden wheat waves are surging. The newly harvested wheat is ground into fragrant flour and enters the kitchens of various households. ……

One out of every eight steamed buns eaten by more than 1.3 billion people in China comes from the wheat variety "Bainong Aikang 58", which is known as "the first wheat in Huanghuai". It is "Mai Da" Ru Zhengang who successfully cultivated this new wheat variety. He is the vice president of the School of Life Science and Technology of Henan University of Science and Technology, the director of the Henan Hybrid Wheat Engineering Technology Research Center, and the chief expert of wheat disease and pest resistance breeding in Henan Province.

Ru Zhengang often said: "As an agricultural science and technology worker, you can’t help farmers increase production and income. You are nothing!" His lifelong aspiration is to fill the granary of China with the power of science and technology.

Change the world with a "go against the sky wheat seed"

Food is scarce and farming is difficult. These childhood memories make Ru Zhengang have an indescribable feeling for wheat. He has always had a "wheat dream", "We must have enough food in Chinese, and the granary is full of our own wheat".

In 1981, Ru Zhengang, who graduated from agronomy, was selected by Professor Huang Guangzheng, a national expert who was famous in the breeding field at that time and won the second prize of national invention, and "pulled into" the breeding industry. Since then, it has been persistent for 36 years.

In order to find the root of the problem of wheat growth, Ru Zhengang ate and lived in the wheat field for several days. In order to ensure the accuracy of the data, he took the research team to manually thresh one by one; In order to understand the growth of wheat in various places, he traveled almost every wheat producing area in China.

In the process of breeding new wheat varieties such as "Aikang 58", Ru Zhengang explored and created a set of nearly complete scientific methods, theoretical systems and scientific research equipment and breeding platform established from it. In his breeding base, from the molecular biology laboratory to the artificial climate room, to the intelligent greenhouse, and then to the outdoor experimental field, it takes only a few minutes to be fully prepared. It is these few minutes’ path that shortens the time of wheat breeding by six years.

Ruzhengang successively cultivated and popularized many varieties such as "Bainong 62", "Bainong 64", "Bainong 160" and "Bainong Aikang 58", and the wheat varieties with stable and high yield filled the granaries of China, which also made the people happy. Ruzhengang has become an out-and-out "God of Grain".

The inspiration for scientific research propositions comes from ordinary people.

"All my scientific research topics and the inspiration and source of technological innovation come from ordinary people." Ru Zhengang traveled all over the country in most wheat fields, and no matter where he went, he never forgot to ask the villagers to "find fault" with their own seeds.

Can wheat be high-yielding and lodging-resistant? Can wheat be planted whenever it wants? The ears of wheat are big, can you make more grains? There are too many ears, can you make the straw shorter? The wheat straw is short, can it tolerate barren and drought? … … Seemingly harsh problems are thrown at him from time to time, and if Ru Zhengang gets the treasure, it will eventually turn into his most breakthrough and creative scientific research topic.

Many experts believe that the wheat yield in Huanghuai area of China has reached the "ceiling", and it is "even more difficult" to further increase the yield. Ru Zhengang’s thoughts and vision jumped to the northeast and Guangdong, Fujian and other places, hoping to find a record-breaking "artifact" in these places.

He constantly challenges himself and his limits. "Even though the frost of time has stained my temples and the knife of years has carved my forehead, why don’t I change my mind and be as heroic as yesterday?" Ru Zhengang expressed his ambition to charge for hybrid wheat breeding in poetic language.

Loving wheat is like your own daughter.

Ru Zhengang said that after 36 years of research, Wheat is actually like his daughter. It can understand his words, and he knows how it can be good, what it likes, what it doesn’t like, and how to make it happy.

"When you chat with wheat with your heart, you can feel the power of its life. Although the breeding work has to face failure 90% of the time, every improvement is an exploration of life and a spiritual enjoyment." Ru Zhengang said.

In Ru Zhengang’s view, wheat that can give people full returns, like wheat, is not wheat, but wheat of a work of art.. He wants to cultivate better wheat varieties, serve the strategic needs of modern agricultural production and national food security, and make new contributions to China’s food security and agricultural harvest. (Source: Ministry of Science and Technology)

Original Ugliness & Visualization of Teacher Cat’s Patent Analysis

Citation between patent documents is the information that reflects their technical relevance, including the documents cited by the applicant in the background technology of his patent application, the comparison documents used by the examiner in the examination process, and the evidence documents submitted by the third party when requesting patent invalidation.

Patent citation can be divided into Cited and quoting, also known as Backward citation and Forward citation. The corresponding patent citations are called cited documents and cited documents. Among them, the cited document refers to the reference document cited by the target patent/family, and the cited document refers to the later document cited by the target patent/family. The relationship among the target patent/family, cited documents and cited documents is shown in the table below.

By combing the citation relationship, the undertaking order of technological innovation research and development among patent documents can be established, which can help analysts reproduce the development process of patent technology. It can also be used as auxiliary information to judge the importance of a patent document by counting the cited situation of a patent document, such as the number of cited documents, the technical field of cited documents, the applicant of cited documents, etc. On this basis, we can also combine the information related to patent literature sources such as country, applicant or inventor, so as to judge the historical contribution, technical strength and competitive position of the technology source.

Case 1: the applicant who cited the most important patent US6191007 in the field of 1：FDSOI technology.

The applicant who cited the patent US6191007 the most times.

Chart Source: Zhang Maoyu. Industrial Patent Analysis Report (Volume 50) Advanced Chip Manufacturing Technology [M]. Beijing: Intellectual Property Press, 2017.

The most frequently cited patent application in the field of FDSOI technology is the patent application with publication number of US6191007 filed by Denso in 1998, which was cited 316 times, and all of them were not self-cited. The main technical direction of this patent application is technology, which is to fabricate SOI or super-wave SOI substrates by ion implantation.

The applicant who cited the patent US6191007 the most was Monolithic 3D Inc, and it can be known that the company may have made key research and development in the field of substrate technology of FDSOI following Denso’s technology. At the same time, other applicants who cited this important patent are Micron, Innovative Silicon and IBM, and these applicants are also key applicants or potentially important applicants in the field of FDSOI.

Case 2: The most influential patent applicant of microalgae related technology

The most influential patent applicant for microalgae-related technology

Chart source: WIPO patent landscape report: micro alga-related technologies

The above figure lists the most influential patent applicants for microalgae-related technologies, and provides two indicators to measure the applicant’s influence, one is the number of patent families owned by the applicant, and the other is the Citation Velocity of the applicant’s patents. The patent citation rate in this report refers to the average number of times each patent is cited by other people’s later applications every year, which excludes the applicant’s self-citation. This citation includes Patent examiners’s citation in the review process as a comparison document, and also includes other patent applicants’ use as prior art documents in the background technology of their patent application documents. The higher the number of citations, the greater the influence of the applicant in this field.

Case 3: Patent citation network of patent applicants in the field of quantum metrology and sensing

Patent citation network of patent applicants in the field of quantum metrology and sensing

Chart source: EPO landscape study on patent filing: quantum metrology and sensing

Through citation analysis, we can also see that there is a very close relationship between enterprise applicants and research institution applicants in the field of quantum metrology and sensing in technology research and development. For example, most of Lockheed Martin’s 55 patents cite the patent documents of university applicants, and 17 of them cite the patents of Melbourne University.

Original title: Patent Analysis Method | Patent Citation Analysis

Read the original text

　　(Declaration: The publication of the manuscript of China Newsweek must be authorized in writing)

　　　 Hong Kong Book Fair: A Carnival for Common People to Read.

　　The special status of Hong Kong has made the sales characteristics of Hong Kong’s book industry, which can’t be copied by mainland or overseas book industry.

　　Our reporter/Chen Xiaoping

　　On July 21st, when Typhoon No.3 "Candu" formed in the South China Sea, the 21st Hong Kong Book Fair, which lasted for one week, kicked off at the Hong Kong Convention and Exhibition Center in Victoria Harbour. The coming typhoon has not stopped Hong Kong people’s great enthusiasm for participation. On the overpass leading to the Convention and Exhibition Center in Central Square, Hong Kong people who came to buy books with carts and suitcases jostled each other. Security guards need to take measures to restrict the release, so as to control the flow of people at any time and maintain order.

　　From the 200,000-person attendance of the first book fair in 1990 to the 920,000-person attendance this year, the annual attendance of the Hong Kong Book Fair has been hitting a new high-today, almost one in every seven Hong Kong people goes to the book fair-although this has made the Hong Kong Book Fair a "fair" for books. The Hong Kong Trade Development Council has made this book business stronger and stronger, and such a lively scene is unmatched by Beijing, Shanghai and Chengdu book fairs.

　　Visit book fairs and buy books once a year.

　　From the Wan Chai subway station to the Convention and Exhibition Center, there are all kinds of publishers’ advertisements, book exhibition posters and flags. At the entrance to the venue, people have to wait for the people in front to fully enter the exhibition before releasing the next batch of visitors. It is said that the longest time, the queue was one kilometer, and citizens had to wait for more than 40 minutes to enter the venue.

　　"I really don’t know what supports the enthusiasm of Hong Kong people to visit the book fair," said a Beijing reporter who participated in the Hong Kong book fair for the first time. Seeing such a scene makes people dizzy, and if the goal of buying books is not clear, it is very painful to find a book in the book fair, just like looking for a needle in a haystack.

　　Including Chinese and English booksellers (bookstores) across the Taiwan Strait and three places, as well as foreign language books from many countries, all publishing houses and bookstores directly enter the venue to set up booths to sell books. Just like the temple fair in Beijing, there are constant shouting and selling in the venue, and there are even booths selling books with banners of "20% off for one book, 30% off for six books and 6.5% off for ten books".

　　On the 22nd, the second day of the book fair, the storm, accompanied by lightning, did not stop Hong Kong people from buying books at the book fair. From time to time, I see book buyers with suitcases, and most of them are mainstream bestsellers. Teenagers prefer "light novels", while the elderly prefer health books. The so-called "light novel" refers to the combination of novels and cartoons. It is a kind of entertaining literary book, which tells stories with cartoons, pays attention to pictures and has shots, and is mostly imported from Japan.

　　During the summer vacation, the main force during the day is middle school students, and some "light novels" are even sold in bundles. In the evening, the age of book buyers goes up. After dinner on Friday, office workers become the main force of the book fair. On the weekend, married with children’s parent-child group appears at the book fair, and Hong Kong people enjoy the seven-day book carnival as a holiday.

　　It has been 21 years since the Hong Kong Book Fair. Visiting the book fair in these seven days has become an annual habit of Hong Kong people. Many young people don’t usually visit bookstores to buy books. They will save a sum of money to buy books at the annual book fair, and even compare with friends.

　　For this phenomenon, Ma Jiahui, a Hong Kong cultural person, explained: "This is a tragedy in Hong Kong. In Hong Kong, there is not even a decent bookstore, and the usual pace of life is very tight. Ordinary people read and buy books less frequently."

　　Hong Kong people advocate fast food culture, and newspapers and periodicals are the main reading contents of the citizens. Young people in Hong Kong usually don’t like reading, and they are not encouraged to read. They don’t know which bookstore to buy books. Therefore, as Ma Jiahui said, if there is no book fair, young people in Hong Kong may not buy books 365 days a year.

　　Hong Kong Commercial Press is a publishing house with the largest retail bookstore in Hong Kong. It has 21 bookstores in Hong Kong and Macao, and also has a professional English law bookstore. The annual turnover of the whole bookstore is 600 million Hong Kong dollars. However, in charge of such a leading enterprise in the book industry in Hong Kong, managing director Lu Guo also lamented that the book market was difficult to do. Although the flagship store of Hong Kong Commercial Press in Tsim Sha Tsui is one of the bookstores that mainland scholars like to visit in Hong Kong, the bookstore has suffered the fate of moving three times in five years because of the high rent and the owner’s failure to renew the contract.

　　Ma Jiahui said that Hong Kong bookstores were all killed by real estate developers.

　　Readers inside and outside the book fair

　　In February, 1923, Sun Yat-sen gave a speech at the University of Hong Kong, saying that his thought originated in Hong Kong. But four years later, when Lu Xun went to Hong Kong to give a speech, a group of literary youths complained to Lu Xun that Hong Kong was a "desert area" ideologically, and the statement that Hong Kong was a "cultural desert" was widely spread.

　　All along, the Hong Kong Trade Development Council has been organizing book fairs with the idea and concept of business management. From asking stars to take the lead in reading and writing books as a marketing tool, to "the second kind of books and periodicals" with pornographic and violent content becoming the focus of the book fair, and then to the invasion of the tender model photo album into the book fair, which also makes the negative news about the book fair continue every year, and the book fair also expands constantly every year, with the increase of exhibition halls, booths and sales figures of books.

　　In 2005, Fred Lam, the new president of the Hong Kong Trade Development Council, proposed that the Hong Kong Book Fair should pay equal attention to culture and commerce. Fred Lam suggested that the TDC is a commercial organization, not a cultural organization, and it is not good at doing cultural things. "We should find excellent cultural institutions and groups in Hong Kong to do this.". Later, they hired the Hong Kong Arts Development Council, Ming Pao Group, Asia Weekly and other cultural organizations as staff officers, and finally decided to cooperate with Asia Weekly to invite writers and cultural celebrities from three places across the Taiwan Straits to give lectures at the book fair.

　　This year’s book fair also opened the "Hong Kong Writers’ Tour 2010" exhibition area for the first time to promote outstanding local writers in Hong Kong, and followed the example of Frankfurt Book Fair to join the works recitation.

　　This year’s book fair invited more than 90 writers to participate in more than 270 cultural and outreach activities. Among them, invited lecturers from the Mainland include Feng Jicai, He Weifang, Pan Shiyi, Zhang Yihe and Han Han. In addition, the speakers of the "Famous Lectures" include Zhou Guangqian, Ge Liang and Lin Peili from Hongkong, Chen Wenxi, Liu Kexiang, Lan Bozhou and Tang Nuo from Taiwan Province, jade y. chen living in Germany and Du Weiming from the United States.

　　In a lecture hall with less than 200 people, Liang Wendao, a Hong Kong writer, is sharing his creative experience with readers. The audience included old people with white hair, peers from Liang Wendao, and more young people, many of whom came from Guangdong to attend the Hong Kong Book Fair.

　　A local young man in Hong Kong, wearing glasses, T-shirt shorts and a pair of straw flip-flops on his feet, listened carefully and took notes on a single piece of paper. It can be seen that young people like Liang Wendao very much, and listen to the lectures carefully.

　　Liang Wendao said that the characteristic of Hong Kong writers is to do their own things silently and write their own books. It seems that the readers in Hong Kong are the same.

　　But more readers are actually outside the book fair. "I haven’t been to the book fair for a long time. My writing doesn’t need to deal with modern people, but is related to the dead." On the other end of the phone, Huang Canran, a Hong Kong poet and translator, told China Newsweek. He goes to work at five o’clock every afternoon and writes in the early hours of the morning. For him, in this busy morning, the day has just ended.

　　In Hongkong, there is also a group of English-reading people. No one has counted the size of this group, but Ma Jiahui told a story: once he made an appointment for a book review and introduced the Chinese version of Said’s books on music. Later, his friend in the Hong Kong Commercial Press told him that the bookstore kept the original English version of the book for one year and hardly sold a few copies. However, after the book review, the original English version sold 20 copies within a week, while the Chinese translation only sold a few more.

　　Hong Kong books export to domestic market.

　　Since 2003, when the mainland opened free travel for tourists to visit Hong Kong, the Hong Kong Book Fair began to welcome mainland readers. Subsequently, the Hong Kong Book Fair set up a "visiting channel", through which you can get preferential ticket purchase. Through these measures, the organizers attract mainland readers to buy books in Hong Kong. According to the statistics of the Hong Kong Trade Development Council, the number of people who entered the 20th Hong Kong Book Fair through the "visiting channel" reached 10,000 last year, and the organizers thought that a considerable number of mainland tourists should follow Hong Kong friends or queue up for admission. In fact, the number of people from the mainland who went to the Hong Kong Book Fair was far more than that.

　　"Export to domestic market" is one of the characteristics of Hong Kong books. Most of the authors of Chinese works in Hong Kong, especially academic works, come from mainland scholars, and these academic works have returned to the mainland, which has formed a big market, except for local and overseas research institutions. Scholars’ "export" and works’ "domestic sales" are an intriguing structure of the Hong Kong book market.

　　The Chinese University of Hong Kong Press, which has published the works of mainland scholars such as How the Red Sun Rises: The ins and outs of Yan ‘an Rectification Movement by Gao Hua, a professor of history at Nanjing University, and Xu Qingquan, deputy editor-in-chief of Yanhuang Chunqiu, the case of Ding Ling and Chen Qixia’s "anti-Party clique", has gathered a group of excellent mainland scholars’ resources. This university publishing house, which aims at "promoting Chinese and Western cultures and spreading ancient and modern knowledge", is a non-profit academic publishing institution. In the past 30 years, it has published a large number of academic works in both Chinese and English, with authors ranging from Qian Mu and Xu Zhongyue to William Theodore de Bary and Needham. Its topics span from traditional China culture to contemporary China studies, and it has established a stable global sales channel.

　　Gan Qi, president of The Chinese University of Hong Kong Press, told China Newsweek that the press followed the anonymous review system of western university press, and the manuscripts of academic works provided by scholars all over the world must be anonymously reviewed by at least two experts in the industry and submitted to the Academic Books Editorial Committee for final approval before they can be accepted for publication or published after being revised by the author. The editorial department, reviewers and academic committees are integrated to ensure that the manuscript has new ideas or new materials, and in short, it has promoted and contributed on the basis of research in the same field. It is under the guarantee of this system that the publications of this society can maintain the content quality and diversified positions for a long time, which has stimulated the academic thoughts in the mainland.

　　The booths of The Chinese University of Hong Kong Press, Hong Kong Oxford University Press, Hong Kong Commercial Press and Hong Kong Sanlian Bookstore are still the favorite bookstall for mainland readers. ★

Compared with previous years, this year’s 618 is still a lot of excitement. As the first mega-event promotion node after the lifting of the epidemic control, it is also the 20th anniversary of the founding of JD.COM. At the party on June 18th, the new CEO of JD.COM, Xu Ran, Chairman of Gree Electric, Dong Mingzhu and others all attended.

At the party, Dong Mingzhu also announced that Gree Electric will cooperate with JD.COM in all categories, and strive to bring better products to users. At the party, Dong Mingzhu, as always, advertised his products:"Gree has been striving to provide better products. After all, only Gree’s air conditioners in the world don’t blow people."

Source: Gree

When it comes to air conditioning, the best-selling brands in everyone’s impression are traditional white goods manufacturers such as Gree, Midea and TCL, among which Gree is famous for focusing on the air conditioning market. It is estimated that many people still remember the advertising words "Gree, master the core technology".

There is a saying that Gree air conditioners do sell well. In JD.COM’s air conditioner sales list, Gree is the manufacturer with the most products in the top ten, and only two air conditioners with a price of more than 3,000 yuan are Gree. In Tmall’s hot-selling list, Gree is also on the list.

What did Dong Mingzhu say: "Gree air conditioners don’t blow people"? Does Gree really rely on this to win the recognition of users?

Air conditioning doesn’t blow people, what black technology?

For Xiao Lei, who lives in the south, air conditioning is a life-saving tool in summer. Since April in Guangzhou, the temperature may be higher than 30 degrees, and in the next six months, it is basically normal for the highest temperature to exceed 30 degrees. It can be said that the time of blowing air conditioning is close to half a year.

Friends who often blow air conditioners know that although the air conditioner is good, it is uncomfortable to blow it too much, especially when the air outlet of the air conditioner is facing you. Even in hot summer, as long as the operation of the air conditioner is still normal, you will start looking for the air conditioner in less than 10 minutes to see if you can change the wind direction of the air conditioner and stop blowing it on your head.

The cold air of air conditioner blowing directly on the human body will cause the somatosensory temperature to drop rapidly, and it only takes a short time for you to feel the coldness like winter in summer. Many netizens even bluntly said that direct air-conditioning blowing will give them headaches. Sometimes they forget to adjust the air-conditioning wind direction before going to bed, and get up the next day with a headache and a cold.

Source: VEER

Gree’s propaganda really poked a lot of people’s pain points. After all, if you can make yourself sleep more comfortably at the same price, why not?

Generally speaking, the design of "not blowing people" is called "soft wind" in the industry, and there are many brands promoting the function of soft wind. Xiaomi, TCL and other brands all have products featuring the function of "soft wind". Generally speaking, it is realized by the design of soft wind plate and upper blowing. As long as the air duct is changed, the demand of "air conditioning does not blow people" can be easily realized.

However,What Dong Mingzhu wants to say is obviously more than this. What she said "air conditioning doesn’t blow people" may be more a summary of Gree air conditioning’s technical strength, product design and user demand.Technically speaking, the long-term cold air blowing directly is largely due to the lack of refrigeration capacity of air conditioners, which leads to the inability to cool the room quickly and has to extend the cooling time.

Source: VEER

The "core technology" that Gree has been promoting actually refers to Gree’s air conditioning compressor technology. As the core of air conditioning, the performance of the compressor itself directly determines the cooling and heating effects of air conditioning. In some real-life tests, Gree’s air conditioners are indeed among the best in cooling speed.

Simply put, just let the room reach the set temperature in a short time, then the air conditioner can enter the maintenance mode with low power consumption, and only need to keep the room temperature with low air volume. If the cold wind blows for a short time, it will naturally not give people a strong coolness, which coincides with the requirement of "not blowing people".

More efficient air-conditioning compressor, with the design of flexible air plate and upper air outlet, makes Gree air-conditioning give users a better experience when cooling. Perhaps this is what Dong Mingzhu said, "Only Gree’s air conditioners don’t blow people", and behind it is also the confidence in Gree’s technology and products.

However, whether Gree air conditioners sell well is because they don’t blow people, I’m afraid there is still a question mark.

Which air conditioners are more popular in this 618?

Writing here, Xiao Lei can’t help wondering, what are the most popular air conditioners in 618? What are the functions of the new air conditioner now? Judging from the total sales list of JD.COM, the top three are Gree, Xiaomi and Midea, and their prices are all below 3,000 yuan, all of which are 1.5-horse hanging air conditioners.

Source: JD.COM

Judging from the total sales record of the list, Gree and Xiaomi are cliff-leading, both of which have sold more than 200,000 pieces. It is not an exaggeration to say that these two products are the most popular air conditioners of 618. On the product introduction page,After a brief summary, Xiao Lei found that the selling points of the two are actually very similar: silence, rapid refrigeration, frequency conversion and power saving, and self-cleaning..

The biggest difference between the two is that Xiaomi, who has been deeply involved in the field of smart home appliances, has added a remote Zhilian function to his air conditioner, which can be remotely controlled through apps such as Mijia, which is much more convenient than traditional air conditioners, even if he forgets to turn off the air conditioner when going out, he can also remotely operate it. Gree, on the other hand, doesn’t support it, and it needs the help of an additional infrared remote control gateway.

Generally speaking, the functions of the two air conditioners are very similar. In the past two years, the internal and external machines with special functions were self-cleaning. Now, they have become the standard of two thousand yuan air conditioners, which makes people feel a little overwhelmed by the air conditioning industry. Moreover, in Internet home appliance brands, intelligent interconnection has become a standard product, but traditional home appliance manufacturers often only carry intelligent interconnection systems on high-end product lines.

Looking at other products in the list, the functions are basically the same, and the main selling points are very similar. As for the biggest reason to guide users to make choices, I am afraid it is price and brand power. In terms of price, it can be seen that except Gree, most of the hot-selling air conditioners are between 2,000 and 3,000 yuan, while Xiaomi is the cheapest 1.5 air conditioners on the list with a bottom of 1,879 yuan.

Basically, at present, when users choose air conditioners, they still value power saving, power, durability, etc., and have low requirements for some new functions.Of course, there are also some products with "new functions" in the list. For example, Haier’s Jingyue series is equipped with intelligent light sense sleep protection function, which will automatically adjust the buzzer and indicator brightness of the air conditioner after turning off the lights to ensure that the user’s sleep is not disturbed.

Source: JD.COM

From the actual experience, it may be a function that is better than nothing for most people, but it is of great significance to some sensitive friends with poor sleep quality. In addition, in this year’s air-conditioning market, there are many more products advertised with functions such as "fresh air" and "plasma sterilization", and some high-end users will also consider the extra skills of air-conditioning.

In the high-end air-conditioning market, air-conditioning is no longer a simple appliance for cooling and heating. Some users also hope that it can also serve as a new fan, air purifier and other products to keep indoor air clean. The pursuit of health by users is becoming a new direction in the high-end air-conditioning market.

In addition, intelligent voice control, modular customization and other functions have begun to appear one after another. In the high-end market, these new designs and functions are good ways to attract users.

However, on the whole, most manufacturers are still doing "icing on the cake" before there is a big change in the air-conditioning market today. And in most cases, a 2000-3000 yuan on-hook can meet the cooling/heating needs of the room. As for those extra functions, to be honest, it is not as attractive as reducing the price in 500 yuan.

　　At 17: 00 on December 28th, the Information Office of Xi ‘an Municipal Government held a press conference on the joint prevention and control of epidemic situation in COVID-19 (Game 39), attended by Lv Yongpeng, deputy director of Xi ‘an Health and Wellness Committee, Yang Yongtao, deputy head of Chang ‘an District Government, and Guo Xiaohui, deputy director of High-tech Zone Management Committee, to report the latest situation of epidemic prevention and control in Xi ‘an.

　　The press conference revealed that starting from December 28, Yanta District, Chang ‘an District and High-tech Zone will conduct a regional nucleic acid screening every day.

　　At the press conference, Lv Yongpeng, deputy director of Xi ‘an Health and Health Commission, introduced that at 12 o’clock on December 27th, Xi ‘an started a new round of nucleic acid screening. By 12 o’clock on the 28th, a total of 12,317,000 people had been sampled, and the result was 11,347,800.

　　In this round of nucleic acid screening, a total of 5,077 sampling points and 11,669 sampling stations were set up, with more than 31,000 sampling personnel and 132,900 service support personnel, with a daily detection capacity of 1.6 million tubes. The workflow of each sampling point is standardized, guiding and persuading the masses to keep "one meter line" and scanning code, so that the sampling work runs efficiently.

　　With the effective organization of staff and the active cooperation of citizens and friends, the efficiency of nucleic acid sampling has been greatly improved. From 12: 00 to 20: 00 on the 27th, a total of 11,080,800 people were sampled, and more than 11 million people were sampled in 8 hours. Yanta District, Chang ‘an District and High-tech Zone will conduct nucleic acid screening once a day from December 28th. According to the situation, Lianhu District will increase the frequency of nucleic acid screening in the whole region; 1250 sampling personnel were transferred from other districts, counties and development zones to support nucleic acid screening in the above four districts, counties and development zones.